ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021
Evaluation of emergency departments visits in patients treated with immune checkpoint inhibitors.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Drivers of Emergency Department Use Among Oncology Patients in the Era of Novel Cancer Therapeutics: A Systematic Review.The oncologist · 2023Pooled it
- Self-efficacy as a mediator between digital health literacy and self-care behaviors in older adults with cancer undergoing chemotherapy.Asia-Pacific journal of oncology nursing · 2026Article
- Novel Systemic Anticancer Treatments and Health Services Use at the End of Life Among Adults With Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025Article
- Clinical characteristics of patients requiring emergency hospitalization due to immune-related adverse events: a retrospective study.Journal of pharmaceutical health care and sciences · 2024Article
- Evaluation of emergency department visits and immune-related adverse effects (irAEs) in patients treated with nivolumab.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Risk factors and predictors of immune-related adverse events: implications for patients with non-small cell lung cancer.Expert review of anticancer therapy · 2022Review
- A nationwide survey among emergency physicians and oncologists to improve the management of immune checkpoint inhibitors toxicity.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Poorer baseline performance status is associated with increased thromboembolism risk in metastatic cancer patients treated with immunotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Evaluation of early unplanned readmissions and predisposing factors in an oncology clinic.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe emergency department (ED) is a crucial encounter point in cancer care. Yet, data on the causes of ED visits are limited in patients treated with immune checkpoint inhibitors (ICI). Therefore, we evaluated ED visits in patients treated with ICIs in attempt to determine the predisposing factors.
methodsWe performed a retrospective chart review on adult cancer patients treated with ICIs for any type of cancer in the Hacettepe University Cancer Center. The data on ED visits after the first dose of ICIs to 6 months after the last cycle of ICIs were collected.
resultsA total of 221 patients were included in the study. The mean age was 58.46 ± 13.87 years, and 65.6% of patients were males. Melanoma was the most common diagnosis (27.6%), followed by kidney and lung cancers. Eighty-three of these patients (37.6%) had at least one emergency department (ED) visit. Most of the ED visits were related to symptoms attributable to the disease burden itself, while immune-related adverse events comprised less than 10% of these visits. While baseline Eastern Cooperative Oncology Group performance status, age, polypharmacy, concomitant chemotherapy, eosinophilia, and lactate dehydrogenase levels did not significantly increase the risk, patients with regular opioid use and baseline neutrophilia (> 8000/mm
conclusionIn this study, almost 40% of ICI-treated patients had ED visits. Collaboration with other specialties like emergency medicine is vital for improving the care of patients receiving immunotherapy.
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