Evidence map›Paper›PMID 32851447›Full record

ArticleEuropean radiology2021

Prediction of tumour grade and survival outcome using pre-treatment PET- and MRI-derived imaging features in patients with resectable pancreatic ductal adenocarcinoma.

Vincent Dunet, Nermin Halkic, Christine Sempoux, Nicolas Demartines, Michael Montemurro, John O Prior, Sabine Schmidt

Open access · hybridAbstract read
In one paragraph

Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Revista de neurologia · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Toward diffusion MRI in the diagnosis and treatment of pancreatic cancer.Medical oncology (Northwood, London, England) · 2025
    Review
  8. Article
  9. Clinical Utility ofMedComm · 2025
    Article
  10. Article
  11. Review
  12. EJNMMI research · 2023
    Article
  13. Prognostic value of preoperative [European journal of nuclear medicine and molecular imaging · 2023
    Article
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Vincent DunetDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Nermin HalkicDepartment of Visceral Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Christine SempouxInstitute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Nicolas DemartinesDepartment of Visceral Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Michael MontemurroDepartment of Oncology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
John O PriorDepartment of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital and University of Lausanne, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland. John.Prior@chuv.ch.ORCID http://orcid.org/0000-0003-1429-1374
Sabine SchmidtDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
University of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo perform a correlation analysis between histopathology and imaging in patients with previously untreated pancreatic ductal adenocarcinoma (PDAC) and to determine the prognostic values of clinical, histological, and imaging parameters regarding overall survival (OS), disease-specific survival (DSS), and progression-free survival (PFS).

methodsThis single-centre study prospectively included 61 patients (32 males; median age, 68.0 years [IQR, 63.0-75.0 years]) with histologically confirmed PDAC and following surgical resection who preoperatively underwent

resultsInverse correlations between ADC

conclusionIn previously untreated PDAC, ADC and SUV values are correlated. Combining PET-MRI metrics may help predict PDAC grade and patients' survival. KEY POINTS: • Minimum apparent diffusion coefficient derived from DW-MRI inversely correlates with tumour grade in pancreatic ductal adenocarcinoma. • In pancreatic ductal adenocarcinoma, metabolic tumour volume has been confirmed as a predictive factor for patients' overall survival and disease-specific survival. • Combining PET and MRI metrics may help predict grade and patients' survival in pancreatic ductal adenocarcinoma.

Indexed as

Pancreatic NeoplasmsPositron Emission Tomography Computed TomographyAgedDiffusion Magnetic Resonance ImagingFluorodeoxyglucose F18HumansMagnetic Resonance ImagingMalePositron-Emission TomographyPrognosisRadiopharmaceuticalsRetrospective StudiesFluorodeoxyglucose F18RadiopharmaceuticalsCarcinoma, Pancreatic ductalDiffusion magnetic resonance imagingFluorodeoxyglucose F-18Patient outcome assessmentProgression-free survival

Identifiers

PMID32851447
PMCPMC7813698
OpenAlexW3080141943

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.