Evidence map›Paper›PMID 32851196›Full record

SynthesisWellcome open research2019

Variation in the observed effect of Xpert MTB/RIF testing for tuberculosis on mortality: A systematic review and analysis of trial design considerations.

Eleanor A Ochodo, Nelson Kalema, Samuel Schumacher, Karen Steingart, Taryn Young, Susan Mallett, Jon Deeks, Frank Cobelens, Patrick M Bossuyt, Mark P Nicol and 1 more

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Wellcome open research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Advances in Molecular Diagnosis of Tuberculosis.Journal of clinical microbiology · 2020
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 7 countries.

Eleanor A OchodoDepartment of Global Health, Stellenbosch University, Cape Town, Western Cape, 8000, South Africa.ORCID https://orcid.org/0000-0002-7951-3030
Nelson KalemaInfectious Diseases Institute, Makerere University, Kampala, 22418, Uganda.ORCID https://orcid.org/0000-0002-7118-704X
Samuel SchumacherTuberculosis Department, Foundation for Innovative New Diagnostics, Geneva, 1202, Switzerland.ORCID https://orcid.org/0000-0002-6136-206X
Karen SteingartDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK.
Taryn YoungDepartment of Global Health, Stellenbosch University, Cape Town, Western Cape, 8000, South Africa.ORCID https://orcid.org/0000-0003-2406-081X
Susan MallettNIHR Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Trust, University of Birmingham, Edgbaston, Birmingham, UK.
Jon DeeksNIHR Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Trust, University of Birmingham, Edgbaston, Birmingham, UK.
Frank CobelensAmsterdam Institute for Global Health and Development, Amsterdam University Medical Centers, Amsterdam, 1105 BP, The Netherlands.
Patrick M BossuytDeapartment of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam University Medical Centers, Amsterdam, 1105 AZ, The Netherlands.ORCID https://orcid.org/0000-0003-4427-0128
Mark P NicolSchool of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Western Australia, Perth, WA, 6009, Australia.ORCID https://orcid.org/0000-0002-1366-4805
Adithya CattamanchiDivision of Pulmonary and Critical Care Medicine, University of California San Francisco Medical Center, San Francisco, California, 94110, USA.ORCID https://orcid.org/0000-0002-6553-2601
NIHR Birmingham Biomedical Research Centre · GBWestern Cape Department of Health · ZAAmsterdam Institute for Global Health and Development · NLAmsterdam University Medical Centers · NLFIND · CHInfectious Diseases Institute · UGLiverpool School of Tropical Medicine · GBThe University of Western Australia · AUUniversity of California San Francisco Medical Center · US

Funding

University of California Launching Future Leaders in Global Health Research Training ProgramD43TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIG R COHEN, Sung-Jae Lee · 2017 to 2026
$14.7M
Building Implementation Science Capacity at Makerere University to Strengthen the Response to the HIV/AIDS Epidemic in UgandaD43TW010037 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI KAMYA, MOSES ROBERT, SEMITALA, FRED C · 2015 to 2025
$3.3M
FIC NIH HHS D43 TW009343FIC NIH HHS D43 TW010037Wellcome Trust 109939/Z/15/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diagnostic trialsImpact studiesmethodologyTuberculosis diagnosis

Identifiers

PMID32851196
PMCPMC7438967
OpenAlexW2983742820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.