Evidence map›Paper›PMID 32851160›Full record

ArticleScience advances2020

Altered 3D chromatin structure permits inversional recombination at the

Xiang Qiu, Fei Ma, Mingming Zhao, Yaqiang Cao, Lillian Shipp, Angela Liu, Arun Dutta, Amit Singh, Fatima Zohra Braikia, Supriyo De and 7 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

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  9. Nemo-Dependent, ATM-Mediated Signals from RAG DNA Breaks atJournal of immunology (Baltimore, Md. : 1950) · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Xiang QiuLaboratory of Molecular Biology and Immunology, National Institute on Aging, Baltimore, MD 21224, USA.ORCID 0000-0001-9161-9033
Fei MaLaboratory of Molecular Biology and Immunology, National Institute on Aging, Baltimore, MD 21224, USA.ORCID 0000-0003-0401-0954
Mingming ZhaoLaboratory of Molecular Biology and Immunology, National Institute on Aging, Baltimore, MD 21224, USA.
Yaqiang CaoLaboratory of Epigenome Biology, Systems Biology Center, National Heart Lung and Blood Institute, Bethesda, MD 20892, USA.ORCID 0000-0002-4665-1517
Lillian ShippLaboratory of Molecular Biology and Immunology, National Institute on Aging, Baltimore, MD 21224, USA.ORCID 0000-0001-9332-6488
Angela LiuLaboratory of Molecular Biology and Immunology, National Institute on Aging, Baltimore, MD 21224, USA.ORCID 0000-0003-0498-8784
Arun DuttaLaboratory of Molecular Biology and Immunology, National Institute on Aging, Baltimore, MD 21224, USA.ORCID 0000-0003-0114-0921
Amit SinghLaboratory of Molecular Biology and Immunology, National Institute on Aging, Baltimore, MD 21224, USA.ORCID 0000-0001-9782-306X
Fatima Zohra BraikiaLaboratory of Molecular Biology and Immunology, National Institute on Aging, Baltimore, MD 21224, USA.
Supriyo DeLaboratory of Genetics and Genomics, National Institute on Aging, Baltimore, MD 21224, USA.ORCID 0000-0002-2075-7655
William H WoodLaboratory of Genetics and Genomics, National Institute on Aging, Baltimore, MD 21224, USA.
Kevin G BeckerLaboratory of Genetics and Genomics, National Institute on Aging, Baltimore, MD 21224, USA.ORCID 0000-0002-6794-6656
Weiqiang ZhouDepartment of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, 21205, USA.ORCID 0000-0001-9396-9571
Hongkai JiDepartment of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, 21205, USA.ORCID 0000-0002-6480-0141
Keji ZhaoLaboratory of Epigenome Biology, Systems Biology Center, National Heart Lung and Blood Institute, Bethesda, MD 20892, USA.
Michael L AtchisonDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Ranjan SenLaboratory of Molecular Biology and Immunology, National Institute on Aging, Baltimore, MD 21224, USA.ORCID 0000-0002-1916-3905
National Institute on Aging · USJohns Hopkins University · USNational Heart Lung and Blood Institute · USUniversity of Pennsylvania · US

Funding

Activation and inactivation of VH gene recombinationZIAAG000372 · NIA · NATIONAL INSTITUTE ON AGING · PI SEN, RANJAN · 2009 to 2021
$4.9M
Control of B cell Development by YY1R01AI079002 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ATCHISON, MICHAEL LEE · 2010 to 2020
$4.3M
Big Data Methods for Decoding Gene RegulationR01HG009518 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI JI, HONGKAI · 2018 to 2021
$1.7M
The role of YY1 in constitutive and inducible DNA loop formationR01GM111384 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI ATCHISON, MICHAEL LEE · 2014 to 2017
$1.2M
NHGRI NIH HHS R01 HG009518NIAID NIH HHS R01 AI079002NIGMS NIH HHS R01 GM111384
6 · The paper itself

Abstract

Immunoglobulin heavy chain (

Identifiers

PMID32851160
PMCPMC7428332
OpenAlexW3049527767

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.