Evidence map›Paper›PMID 32851085›Full record

SynthesisBioMed research international2020

The Efficacy of Traditional Chinese Medicine Shoutai Pill Combined with Western Medicine in the First Trimester of Pregnancy in Women with Unexplained Recurrent Spontaneous Abortion: A Systematic Review and Meta-Analysis.

Hui-Fang Li, Qi-Hong Shen, Xiao-Qing Li, Zhang-Feng Feng, Wei-Min Chen, Jia-Hua Qian, Li Shen, Li-Ying Yu, Yi Yang

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  15. The Application of Complementary and Alternative Medicine in Polycystic Ovary Syndrome Infertility.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  16. Article
  17. Article
  18. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hui-Fang LiDepartment of TCM Gynecology, Tongxiang Maternal and Child Health-Care Center, Tongxiang, Zhejiang 314500, China.ORCID https://orcid.org/0000-0002-3635-2337
Qi-Hong ShenDepartment of Anesthesiology, Affiliated Hospital of Jiaxing University, The First Hospital of Jiaxing, Jiaxing, Zhejiang 314000, China.ORCID https://orcid.org/0000-0003-3365-779X
Xiao-Qing LiDepartment of Obstetrics, Tongxiang Maternal and Child Health-Care Center, Tongxiang, Zhejiang 314500, China.
Zhang-Feng FengDepartment of Gynecology, Tongxiang Maternal and Child Health-Care Center, Tongxiang, Zhejiang 314500, China.ORCID https://orcid.org/0000-0003-1680-1454
Wei-Min ChenDepartment of Gynecology, Tongxiang Maternal and Child Health-Care Center, Tongxiang, Zhejiang 314500, China.ORCID https://orcid.org/0000-0003-2864-2024
Jia-Hua QianDepartment of Internal medicine, Tongxiang Maternal and Child Health-Care Center, Tongxiang, Zhejiang 314500, China.
Li ShenDepartment of Nursing, Tongxiang Maternal and Child Health-Care Center, Tongxiang, Zhejiang 314500, China.
Li-Ying YuDepartment of Gynecology, Tongxiang Maternal and Child Health-Care Center, Tongxiang, Zhejiang 314500, China.ORCID https://orcid.org/0000-0003-3855-5434
Yi YangDepartment of TCM Gynecology, Tongxiang Maternal and Child Health-Care Center, Tongxiang, Zhejiang 314500, China.
Jiaxing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundShoutai Pill (STP), a famous classic herbal formula documented in traditional Chinese medicine (TCM), is widely available in China for treating unexplained recurrent spontaneous abortion (URSA). This systematic review and meta-analysis aims at evaluating the efficacy and safety of STP in the first trimester of pregnancy in women with a history of unexplained recurrent spontaneous abortion.

methodsThe following eight databases were searched from their establishment to Dec 31, 2019, for randomized controlled trials (RCTs): PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), the Chinese BioMedical database (CBM), Chinese Scientific Journal Database (VIP), and the Wanfang database. The quality of evidence was estimated by the Grading of Recommendations Assessment, Development, and Evaluation (GRADE).

resultsA total of 12 studies (916 patients) with URSA were contained in this meta-analysis. The forest plot showed that patients treated with Shoutai Pill and western medicine had a significantly lower incidence of early pregnancy loss (RR: 0.42; 95% CI: 0.34-0.52;

conclusionsOur findings suggest that cotreatment with STP and western medicine might be superior to western medicine alone in the first trimester of pregnancy to prevent miscarriage in women with unexplained recurrent spontaneous abortion, and there was no adverse event in the experimental group reported. However, the methodological quality of included RCTs was unsatisfactory; it is necessary to verify its effectiveness with further more standardized researches of rigorous design.

Indexed as

Abortion, HabitualAbortion, SpontaneousChinaCombined Modality TherapyDrugs, Chinese HerbalFemaleHumansLive BirthMedicine, Chinese TraditionalPhytotherapyPregnancyPregnancy Trimester, FirstDrugs, Chinese Herbal

Identifiers

PMID32851085
PMCPMC7436282
OpenAlexW3047974417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.