Evidence map›Paper›PMID 32851000›Full record

ArticleFrontiers in veterinary science2020

A New Cage-Like Particle Adjuvant Enhances Protection of Foot-and-Mouth Disease Vaccine.

Juan Bidart, Claudia Kornuta, Mariela Gammella, Victoria Gnazzo, Ivana Soria, Cecilia Langellotti, Claudia Mongini, Roxana Galarza, Luis Calvinho, Giuliana Lupi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Juan BidartInstituto de Virología e Innovaciones Tecnológicas-IVIT, CICVyA, INTA-CONICET, Hurlingham, Argentina.
Claudia KornutaInstituto de Virología e Innovaciones Tecnológicas-IVIT, CICVyA, INTA-CONICET, Hurlingham, Argentina.
Mariela GammellaInstituto de Virología e Innovaciones Tecnológicas-IVIT, CICVyA, INTA-CONICET, Hurlingham, Argentina.
Victoria GnazzoInstituto Nacional de Medicina Tropical, Puerto Iguazú, Argentina.
Ivana SoriaInstituto de Virología e Innovaciones Tecnológicas-IVIT, CICVyA, INTA-CONICET, Hurlingham, Argentina.
Cecilia LangellottiInstituto de Virología e Innovaciones Tecnológicas-IVIT, CICVyA, INTA-CONICET, Hurlingham, Argentina.
Claudia MonginiInstituto de Virología e Innovaciones Tecnológicas-IVIT, CICVyA, INTA-CONICET, Hurlingham, Argentina.
Roxana GalarzaAgencia de Extensión Rural Chascomus, INTA, Chascomus, Argentina.
Luis CalvinhoEstación Experimental Agropecuaria Rafaela, INTA, Rafaela, Argentina.
Giuliana LupiConsejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.
Valeria QuattrocchiInstituto de Virología e Innovaciones Tecnológicas-IVIT, CICVyA, INTA-CONICET, Hurlingham, Argentina.
Ivan MarciparConsejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.
Patricia ZamoranoInstituto de Virología e Innovaciones Tecnológicas-IVIT, CICVyA, INTA-CONICET, Hurlingham, Argentina.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARInstituto Nacional de Medicina Tropical · ARInstituto Tecnológico de Chascomús · ARNational University of the Littoral · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foot-and-Mouth Disease (FMD) is an acute viral disease that causes important economy losses. Vaccines with new low-cost adjuvants that stimulate protective immune responses are needed and can be assayed in a mouse model to predict their effectiveness in cattle. Immunostimulant Particle Adjuvant (ISPA), also known as cage-like particle adjuvant, consisting of lipid boxes of dipalmitoyl-phosphatidylcholine, cholesterol, sterylamine, alpha-tocopherol, and QuilA saponin, was shown to enhance protection of a recombinant vaccine against

Indexed as

adjuvantFMDVimmune responceISPAprotectionvaccine

Identifiers

PMID32851000
PMCPMC7411152
OpenAlexW3036892293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.