Evidence map›Paper›PMID 32850766›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Wnt Signaling Inhibits High-Density Cell Sheet Culture Induced Mesenchymal Stromal Cell Aging by Targeting Cell Cycle Inhibitor p27.

Ying Xu, Ye Tian, Dongyi Tong, Hao Zhang, Zhengliang Luo, Xifu Shang, Yufeng Dong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ying XuDepartment of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, China.
Ye TianDepartment of Orthopedics, Shengjing Hospital of China Medical University, Shenyang, China.
Dongyi TongDepartment of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, China.
Hao ZhangCenter for Tissue Engineering and Regenerative Medicine, Department of Orthopedic Surgery, Louisiana State University Health Sciences Center, Shreveport, LA, United States.
Zhengliang LuoDivision of Life Sciences and Medicine, Department of Orthopedic Surgery, The First Affiliated Hospital, University of Science and Technology of China, Hefei, China.
Xifu ShangDivision of Life Sciences and Medicine, Department of Orthopedic Surgery, The First Affiliated Hospital, University of Science and Technology of China, Hefei, China.
Yufeng DongCenter for Tissue Engineering and Regenerative Medicine, Department of Orthopedic Surgery, Louisiana State University Health Sciences Center, Shreveport, LA, United States.

Funding

Notch-enriched Mesenchymal Stromal Cells for Bone Allograft RepairR01AR073277 · NIAMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI DONG, YUFENG · 2019 to 2024
$1.6M
NIAMS NIH HHS R01 AR073277
6 · The paper itself

Abstract

Mesenchymal stromal cell senescence and apoptosis have been identified as critical molecular hallmarks in aging. In this study, we used stromal cell sheet culture as an

Indexed as

agingapoptosiscell sheet culturesenescencestromal cell

Identifiers

PMID32850766
PMCPMC7419600

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.