Evidence map›Paper›PMID 32850737›Full record

ReviewFrontiers in bioengineering and biotechnology2020

Cell Reprogramming With CRISPR/Cas9 Based Transcriptional Regulation Systems.

Ksenia M Shakirova, Viktoriia Y Ovchinnikova, Erdem B Dashinimaev

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
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  11. Review
  12. Genetic Analysis Based on CRISPR/Cas9 Technology in Plants.International journal of molecular sciences · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Control of Bacterial Diseases of Banana Using CRISPR/Cas-Based Gene Editing.International journal of molecular sciences · 2022
    Review
  17. Review
  18. Review
  19. Review
  20. Hypoxia-sensitive miRNA regulationFrontiers in cell and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ksenia M ShakirovaFaculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
Viktoriia Y OvchinnikovaFaculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
Erdem B DashinimaevKoltzov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The speed of reprogramming technologies evolution is rising dramatically in modern science. Both the scientific community and health workers depend on such developments due to the lack of safe autogenic cells and tissues for regenerative medicine, genome editing tools and reliable screening techniques. To perform experiments efficiently and to propel the fundamental science it is important to keep up with novel modifications and techniques that are being discovered almost weekly. One of them is CRISPR/Cas9 based genome and transcriptome editing. The aim of this article is to summarize currently existing CRISPR/Cas9 applications for cell reprogramming, mainly, to compare them with other non-CRISPR approaches and to highlight future perspectives and opportunities.

Indexed as

CRISPR/Cas9dCas9genome screeninghuman cell reprogrammingregenerative medicinetransactivator systems

Identifiers

PMID32850737
PMCPMC7399070

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.