ReviewFrontiers in pediatrics2020
When the Cough Does Not Improve: A Review on Protracted Bacterial Bronchitis in Children.
Review in Frontiers in pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07232550 (Biomarkers and Respiratory Omics as New CHildren Opportunities - Study of Clinical Outcomes and Predictivity Evaluation - a Multi-cohort, Multi-center Study), which is not on this map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Biomarkers and Respiratory Omics as New CHildren Opportunities - Study of Clinical Outcomes and Predictivity Evaluation - a Multi-cohort, Multi-center Study
Who cites it
20 citing papers in PubMed, 39 citations in OpenAlex.
- Traditional Chinese medicine combined with conventional Western medicine for chronic cough following respiratory infection in children: a systematic review and meta-analysis.Translational pediatrics · 2026Article
- High rate of pulmonary exacerbations and neutrophilic airway inflammation in children with repaired esophageal atresia with or without tracheoesophageal fistula.Pediatric research · 2026Article
- Bronchoalveolar Results in Young Children with Chronic Lung Symptoms: Lessons Learned from an Allergy-Pulmonology Project Guided by an Updated Mini Review of the Current Literature of Bronchoalveolar Lavage Eosinophilia and Neutrophilia in Normal Children.Children (Basel, Switzerland) · 2026Article
- Analysis of Cough Factors and Quality of Life Score Among Children With Protracted Bacterial Bronchitis: Cross-Sectional Study.JMIR pediatrics and parenting · 2025Article
- Pediatric bronchiectasis-the importance of early diagnosis of children across the chronic wet cough spectrum.Journal of thoracic disease · 2025Review
- Clinical characteristics of infants with protracted bacterial bronchitis: an observational cohort study.Translational pediatrics · 2025Article
- Respiratory microbiota diversity and composition in recurrent protracted bacterial bronchitis: a cross-sectional study.Frontiers in cellular and infection microbiology · 2025Article
- Article
- Traditional Herbal Plants and their Phytoconstituents Based Remedies for Respiratory Diseases: A Review.The open respiratory medicine journal · 2025Review
- Cough in Protracted Bacterial Bronchitis and Bronchiectasis.Journal of clinical medicine · 2024Article
- Chronic Bronchitis in Children and Adults: Definitions, Pathophysiology, Prevalence, Risk Factors, and Consequences.Journal of clinical medicine · 2024Review
- Tic Cough in an Adolescent with Organic Brain Pathology-A Case Report and Literature Review.Brain sciences · 2024Article
- Clinical efficacy of bronchoalveolar lavage in the treatment of small airway diseases in children.Frontiers in pediatrics · 2024Article
- The Respiratory Microbiome in Paediatric Chronic Wet Cough: What Is Known and Future Directions.Journal of clinical medicine · 2023Review
- T2-Low Asthma: A Discussed but Still Orphan Disease.Biomedicines · 2023Review
- Infectious and Inflammatory Pathways to Cough.Annual review of physiology · 2023Review
- Article
- Associated Risk Factors and Diagnostic Value of Fiberoptic Bronchoscopy for Protracted Bacterial Bronchitis in Children.International journal of clinical practice · 2023Article
- Non-Cystic Fibrosis Bronchiectasis in Pediatric Age: A Case Series in a Metropolitan Area of Northern Italy.Children (Basel, Switzerland) · 2022Article
- Predictors of the Development of Protracted Bacterial Bronchitis following Presentation to Healthcare for an Acute Respiratory Illness with Cough: Analysis of Three Cohort Studies.Journal of clinical medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic cough is defined as a daily cough that persists longer than 4 weeks. Protracted bacterial bronchitis (PBB) is a common cause of chronic wet cough in preschool children with no symptoms or signs of other specific causes, and resolution usually follows a 2-week course of an appropriate oral antibiotic. The diagnosis is mainly clinical; generally, no instrumental examinations are necessary. The most common bacteria found in the bronchoalveolar lavage (BAL) of subjects with PBB include
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.