ArticleFrontiers in pediatrics2020
Changes in Human Milk Immunoglobulin Profile During Prolonged Lactation.
Article in Frontiers in pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 107 citations in OpenAlex.
- The Breast Milk Immunoglobulinome.Nutrients · 2021Pooled it
- Breastfeeding and COVID-19: From Nutrition to Immunity.Frontiers in immunologyPooled it
- COVID-19 mRNA vaccine and antibody response in lactating women: a prospective cohort study.BMC pregnancy and childbirth · 2021Trial
- Myelin Oligodendrocyte Glycoprotein Antibodies in Breast Milk in a Lactating Woman With Severe Enterovirus-Associated MOGAD.Neurology(R) neuroimmunology & neuroinflammation · 2026Article
- Early-Life Biomarkers in Food Allergy Development: A Systematic Review of Immunological and Intestinal Pathways.Biomedicines · 2026Review
- Low serum immunoglobulin levels in pediatric atopic dermatitis: association with disease severity and exploratory scores.European journal of pediatrics · 2026Article
- Safety and efficacy of COVID-19 vaccines in pregnant and lactating women: a comprehensive review.Inflammopharmacology · 2026Review
- Breast milk antibody Fc signatures track with HIV transmission during breastfeeding in ART-naïve mothers.iScience · 2026Article
- Variability in the Composition and Antioxidant Status of Milk of Polish Women Breastfeeding up to 2 Years.Nutrients · 2026Article
- Coordination Between Treg Cells and Bifidobacterium in the Immune-Bacterial Network of Human Colostrum.Journal of immunology research · 2026Article
- Breastfeeding beyond infancy supports adequate growth, development, and nutritional intake.Pediatric research · 2026Article
- Global seroprevalence of neutralizing and total antibodies against AAV vectors and their impact on the clinical gene therapy landscape: a scoping review.Frontiers in medicine · 2026Review
- Adiposity-dependent adipokine-immunoglobulin interplay in mature breast milk.Frontiers in endocrinology · 2026Observational
- Microbiome in heritage: how maternal microbiome transmission impacts next generation health.Microbiome · 2025Review
- The Gut Microbiota of Peruvian Children Under the Age of Two During the Complementary Feeding Period.International journal of environmental research and public health · 2025Article
- Breast milk IgG engages the mouse neonatal immune system to instruct responses to gut antigens.Science (New York, N.Y.) · 2025Article
- Lactoferrin and SIgA Concentrations in Human Milk of SARS-CoV-Infected Mothers-Polish Cohort Study.Nutrients · 2025Article
- Impact of Maternal Exposure to SARS-CoV-2 on Immunological Components of Breast Milk.International journal of molecular sciences · 2025Review
- Human milk whey proteins: Constituents, influencing factors, detection methods, and comparative analysis with other sources.Food chemistry: X · 2025Review
- Day/night fluctuations of breast milk bioactive factors and microbiome.Frontiers in nutrition · 2025Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mother's milk immunoglobulins (Igs) delivered to infants during breastfeeding are crucial in shaping and modulating immature infants' immune system and provide efficient protection against pathogens. The aim of the study was to evaluate the immunoglobulin concentrations in milk of 116 lactating mothers over prolonged lactation from the 1st to the 48th month using the ELISA method. The concentration of proteins, SIgA and IgG, but not IgM, showed a positive correlation (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.