ReviewFrontiers in cellular and infection microbiology2020
Do Mixed-Species Biofilms Dominate in Chronic Infections?-Need for
Review in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 48 citations in OpenAlex.
- Species-specific chlorine resistance and biofilm regulation by extracellular polymeric substances and quorum sensing in drinking water pipeline bacteria.Applied and environmental microbiology · 2026Article
- Peroxidase-mimicking chitosan/dextran-coated cobalt ferrite-graphene oxide nanozyme enhances hydrogen peroxide-mediated killing of cariogenic pathogens in dental biofilm models.Scientific reports · 2026Article
- Microbial-Responsive Wound Dressings Based on Biopolymer Degradation Strategy for Detecting Bacterial Infections.ACS applied materials & interfaces · 2026Article
- Discovering a green pesticide candidate for controlling bacterial plant disease: 1,2,3,4-tetrahydro-β-carboline as a potential biofilm inhibitor.RSC advances · 2025Article
- Polymicrobial biofilms in chronic rhinosinusitis: a scoping review.Journal of medical microbiology · 2025Article
- Lectins as Natural Antibiofilm Agents in the Fight Against Antibiotic Resistance: A Review.Molecules (Basel, Switzerland) · 2025Review
- Enhanced virulence of mixed-species Candida biofilms isolated from intragastric balloon patient: insights from larval model.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Mechanisms of S. agalactiae promoting G. vaginalis biofilm formation leading to recurrence of BV.NPJ biofilms and microbiomes · 2024Article
- Review
- Understanding the multifaceted etiopathogenesis of foot complications in individuals with diabetes.World journal of clinical cases · 2023Review
- Anti-Biofilm Efficacy of Commonly Used Wound Care Products in In Vitro Settings.Antibiotics (Basel, Switzerland) · 2023Article
- Chenodeoxycholic Acid-Amikacin Combination Enhances Eradication of Staphylococcus aureus.Microbiology spectrum · 2023Article
- Investigation of the Mechanism and Chemistry Underlying Staphylococcus aureusJournal of bacteriology · 2022Article
- Anti-biofilm activity of caffeine against uropathogenic E. coli is mediated by curli biogenesis.Scientific reports · 2022Article
- Biofilm Formation by Chromoblastomycosis FungiJournal of fungi (Basel, Switzerland) · 2022Article
- Antimicrobial Resistance and Biofilms Underlying Catheter-Related Bloodstream Coinfection byAntibiotics (Basel, Switzerland) · 2022Article
- The structure-function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment.FEMS microbiology reviews · 2022Review
- Enhanced Antibiotic Tolerance of anMicroorganisms · 2022Article
- Emerging Concern with Imminent Therapeutic Strategies for Treating Resistance in Biofilm.Antibiotics (Basel, Switzerland) · 2022Review
- Immunometabolism in biofilm infection: lessons from cancer.Molecular medicine (Cambridge, Mass.) · 2022Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic infections present a serious economic burden to health-care systems. The severity and prevalence of chronic infections are continuously increasing due to an aging population and an elevated number of lifestyle related diseases such as diabetes. Treatment of chronic infections has proven difficult, mainly due to the presence of biofilms that render bacteria more tolerant toward antimicrobials and the host immune response. Chronic infections have been described to harbor several different bacterial species and it has been hypothesized that microscale interactions and mixed-species consortia are present as described for most natural occurring biofilms i.e., aquatic systems and industrial settings, but also for some commensal human biofilms i.e., the mouth microbiota. However, the presence of mixed-species biofilms in chronic infections is most often an assumption based on culture-based methods and/or by means of molecular approaches, such as PCR and sequencing performed from homogenized bulk tissue samples. These methods disregard the spatial organization of the bacterial community and thus valuable information on biofilm aggregate composition, spatial organization, and possible interactions between different species is lost. Hitherto, only few studies have made visual
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.