Evidence map›Paper›PMID 32850381›Full record

ArticleFrontiers in oncology2020

Knockdown of CYP24A1 Aggravates 1α,25(OH)

Ping Wang, Jiming Xu, Weijing You, Yongfeng Hou, Shuiliang Wang, Yujie Ma, Jianming Tan, Zengli Zhang, Wentao Hu, Bingyan Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. 1α,25(OH)Journal of endocrinological investigation · 2025
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ping WangDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou, China.
Jiming XuDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou, China.
Weijing YouDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou, China.
Yongfeng HouState Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Shuiliang WangFujian Key Laboratory of Transplant Biology, 900 Hospital of the Joint Logistics Team, Fuzhou, China.
Yujie MaFujian Key Laboratory of Transplant Biology, 900 Hospital of the Joint Logistics Team, Fuzhou, China.
Jianming TanFujian Key Laboratory of Transplant Biology, 900 Hospital of the Joint Logistics Team, Fuzhou, China.
Zengli ZhangDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou, China.
Wentao HuState Key Laboratory of Radiation Medicine and Protection, Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, School of Radiation Medicine and Protection, Soochow University, Suzhou, China.
Bingyan LiDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou, China.
Soochow University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial-mesenchymal transition (EMT) bestows cancer cells with motile and invasive properties. But for ovarian tissues, EMT plays a physiological role in the postovulatory repair of ovary surface epithelial (OSE) cells. Accumulating data indicated that 1α,25(OH)

Indexed as

1α,25(OH)2D3CYP24A1epithelial–mesenchymal transitioninvasionmigration

Identifiers

PMID32850381
PMCPMC7403498
OpenAlexW3046087118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.