Evidence map›Paper›PMID 32850070›Full record

ArticleJournal of community hospital internal medicine perspectives2020

' Loperamide overdose induces ventricular tachycardia with catastrophic outcomes'.

Zain Ali, Umer Shoukat, Mariya Khan, Sohaib Roomi, Waqas Ullah

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of community hospital internal medicine perspectives, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Rising toxicity of the antidiarrheal drug: loperamide in Pakistan.Annals of medicine and surgery (2012) · 2023
    Article
  3. In Silico Drug Repurposing Approach: Investigation ofMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Zain AliPhysician, Internal Medicine, Abington Memorial Hospital, Abington, PA, USA.ORCID 0000-0002-5457-9420
Umer ShoukatPhysician, Internal Medicine, Abington Memorial Hospital, Abington, PA, USA.
Mariya KhanCivil Hospital, Karachi, Dow University of Health Sciences, Karachi, Pakistan.
Sohaib RoomiResident Physician, Internal Medicine, Abington Memorial Hospital, Abington, PA, USA.ORCID 0000-0001-5998-9309
Waqas UllahPhysician, Internal Medicine, Abington Memorial Hospital, Abington, PA, USA.ORCID 0000-0002-4850-0309
Abington Memorial Hospital · USCivil Hospital Karachi · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loperamide is a widely available, over-the-counter medication. The advent of the opioid epidemic has seen cases of loperamide overdose being reported. The common side effects of the medication can be relatively benign, but at high doses, loperamide can precipitate life-threatening arrhythmias. Our case highlights rare side effects of loperamide overdose inducing ventricular tachycardia, with unfavorable consequences. This case emphasizes that the distribution and availability of this medication should be restricted, to be a prescription drug, to prevent overdose and adverse outcomes.

Indexed as

arrhythmiascardiotoxicityLoperamide overdoseQT prolongationtorsade de Pointesventricular tachycardia

Identifiers

PMID32850070
PMCPMC7426977
OpenAlexW3034328976

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.