Evidence map›Paper›PMID 32849998›Full record

ArticleOxidative medicine and cellular longevity2020

The Activation of Phosphatidylserine/CD36/TGF-

Lei Huang, Hailiang Tang, Prativa Sherchan, Cameron Lenahan, Warren Boling, Jiping Tang, John H Zhang

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Impact Induces Phagocytic Defect in Reactive Microglia.bioRxiv : the preprint server for biology · 2025
    Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Lei HuangDepartment of Neurosurgery, Loma Linda University, 11234 Anderson Street, Loma Linda, CA 92354, USA.ORCID https://orcid.org/0000-0002-7211-8337
Hailiang TangDepartment of Neurosurgery, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Rd, Jing'an District, Shanghai 201206, China.ORCID https://orcid.org/0000-0003-1852-3128
Prativa SherchanDepartment of Physiology and Pharmacology, Loma Linda University, 11041 Campus Street, Loma Linda, CA 92354, USA.ORCID https://orcid.org/0000-0002-2909-283X
Cameron LenahanDepartment of Physiology and Pharmacology, Loma Linda University, 11041 Campus Street, Loma Linda, CA 92354, USA.ORCID https://orcid.org/0000-0002-2979-7979
Warren BolingDepartment of Neurosurgery, Loma Linda University, 11234 Anderson Street, Loma Linda, CA 92354, USA.ORCID https://orcid.org/0000-0003-3935-9275
Jiping TangDepartment of Physiology and Pharmacology, Loma Linda University, 11041 Campus Street, Loma Linda, CA 92354, USA.ORCID https://orcid.org/0000-0002-2392-9280
John H ZhangDepartment of Neurosurgery, Loma Linda University, 11234 Anderson Street, Loma Linda, CA 92354, USA.ORCID https://orcid.org/0000-0002-4319-4285
Loma Linda University · USFudan University · CN

Funding

Vascular Biology Core FacilityP01NS082184 · NINDS · LOMA LINDA UNIVERSITY · PI PEARCE, WILLIAM J. · 2014 to 2018
$6.1M
Mechanisms of Hyperbaric Oxygen Induced Brain ProtectionR01NS043338 · NINDS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI ZHANG, JOHN H · 2004 to 2014
$3.0M
Crotalus Snake Venom Preconditioning to Prevent Surgical Brain InjuryR01NS084921 · NINDS · LOMA LINDA UNIVERSITY · PI ZHANG, JOHN H · 2014 to 2018
$1.7M
NINDS NIH HHS P01 NS082184NINDS NIH HHS R01 NS043338NINDS NIH HHS R01 NS084921
6 · The paper itself

Abstract

Neuroinflammation plays an important pathological role in experimental surgical brain injury (SBI). Apoptotic associated with phosphatidylserine (PS) externalization promotes anti-inflammatory mediator TGF-

Indexed as

AnimalsBrainBrain EdemaBrain InjuriesCD36 AntigensInflammationIntraoperative ComplicationsIsofluraneLiposomesMaleNeuroprotective AgentsPhosphatidylserinesRats, Sprague-DawleyRNA, Small InterferingSignal TransductionTransforming Growth Factor beta1CD36 AntigensIsofluraneLiposomesNeuroprotective AgentsPhosphatidylserinesRNA, Small InterferingTransforming Growth Factor beta1

Identifiers

PMID32849998
PMCPMC7441426
OpenAlexW3048428044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.