ArticleBiomicrofluidics2020
Luer-lock valve: A pre-fabricated pneumatic valve for 3D printed microfluidic automation.
Article in Biomicrofluidics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 7 citations in OpenAlex.
- Programmed Internal Reconfigurations in a 3D-Printed Mechanical Metamaterial Enable Fluidic Control for a Vertically Stacked Valve Array.Advanced functional materials · 2024Article
- Critical Study on the Tube-to-Chip Luer Slip Connectors.Frontiers in medical technology · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
3D printed microfluidic devices are made of stiff and easy-to-fatigue materials and hence are difficult to have robust pneumatic valves. In this work, we describe a type of prefabricated polydimethylsiloxane (PDMS) valves, named the "Luer-lock" valve, which can be incorporated in 3D printed microfluidic devices utilizing the Luer-lock mechanism. Luer-lock design has been adopted for fluidic connections worldwide; it is facile, reliable, and inexpensive. To take advantage of the Luer-lock design, we added "valve ports" to our 3D printed microfluidic devices; prefabricated PDMS valve modules could be embedded into these valve ports, in a leak-free manner, by screwing tight the Luer-locks. In the experiment, we succeeded in fabricating pneumatic valves with a footprint diameter of 0.8 mm and verified the functionality of these valves with a shut-off pressure of 140 mbar and a maximal switching frequency of ∼1 Hz. As a demonstration, we show the serial encoding of core-shell hydrogel microfibers using the Luer-lock valves. Since the Luer-lock valves can be mass-produced and the CAD model of Luer-locks can be easily distributed, we believe that our approach has the potential to be easily adopted by researchers around the globe.
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Registered trials
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