Evidence map›Paper›PMID 32849789›Full record

ArticleFrontiers in genetics2020

VisTCR: An Interactive Software for T Cell Repertoire Sequencing Data Analysis.

Qingshan Ni, Jianyang Zhang, Zihan Zheng, Gang Chen, Laura Christian, Juha Grönholm, Haili Yu, Daxue Zhou, Yuan Zhuang, Qi-Jing Li and 1 more

Abstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. TCR_Explore: A novel webtool for T cell receptor repertoire analysis.Computational and structural biotechnology journal · 2023
    Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qingshan NiBiomedical Analysis Center, Army Medical University, Chongqing, China.
Jianyang ZhangBiomedical Analysis Center, Army Medical University, Chongqing, China.
Zihan ZhengBiowavelet Ltd., Chongqing, China.
Gang ChenBiomedical Analysis Center, Army Medical University, Chongqing, China.
Laura ChristianDepartment of Immunology, Duke University Medical Center, Durham, NC, United States.
Juha GrönholmMolecular Development of the Immune System Section, NIAID Clinical Genomics Program, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Haili YuBiomedical Analysis Center, Army Medical University, Chongqing, China.
Daxue ZhouBiomedical Analysis Center, Army Medical University, Chongqing, China.
Yuan ZhuangDepartment of Immunology, Duke University Medical Center, Durham, NC, United States.
Qi-Jing LiDepartment of Immunology, Duke University Medical Center, Durham, NC, United States.
Ying WanBiomedical Analysis Center, Army Medical University, Chongqing, China.

Funding

Basic Immunology Training ProgramT32AI052077 · NIAID · DUKE UNIVERSITY · PI KRANGEL, MICHAEL S · 2002 to 2024
$4.2M
NIAID NIH HHS T32 AI052077
6 · The paper itself

Abstract

Recent progress in high throughput sequencing technologies has provided an opportunity to probe T cell receptor (TCR) repertoire, bringing about an explosion of TCR sequencing data and analysis tools. For easier and more heuristic analysis TCR sequencing data, we developed a client-based HTML program (VisTCR). It has a data storage module and a data analysis module that integrate multiple cutting-edge analysis algorithms in a hierarchical fashion. Researchers can group and re-group samples for different analysis purposes by customized "Experiment Design File." Moreover, the VisTCR provides a user-friendly interactive interface, by all the TCR analysis methods and visualization results can be accessed and saved as tables or graphs in the process of analysis. The source code is freely available at https://github.com/qingshanni/VisTCR.

Indexed as

analysis tooldata analysisGraphic user interfaceT cell repertoireT cell sequencing

Identifiers

PMID32849789
PMCPMC7416706

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.