Evidence map›Paper›PMID 32849617›Full record

ArticleFrontiers in immunology2020

Deletion of

Audrey Bernut, Catherine A Loynes, R Andres Floto, Stephen A Renshaw

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Cystic fibrosis: insights from zebrafish models.Disease models & mechanisms · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Wound repair and immune function in theFrontiers in cellular and infection microbiology · 2025
    Review
  8. Evolution and host-specific adaptation ofScience (New York, N.Y.) · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. DUOX2 regulates secreted factors in virus-infected respiratory epithelial cells that contribute to neutrophil attraction and activation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  15. Neutrophil reverse migration.Journal of inflammation (London, England) · 2022
    Review
  16. Roscovitine WorsensAmerican journal of respiratory cell and molecular biology · 2022
    Article
  17. The Effect of CFTR Modulators on Airway Infection in Cystic Fibrosis.International journal of molecular sciences · 2022
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Audrey BernutDepartment of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, United Kingdom.
Catherine A LoynesDepartment of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, United Kingdom.
R Andres FlotoMolecular Immunity Unit, Department of Medicine, University of Cambridge, Francis Crick Avenue, Cambridge Biomedical, Cambridge, United Kingdom.
Stephen A RenshawDepartment of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, United Kingdom.
University of Sheffield · GBMRC Laboratory of Molecular Biology · GB

Funding

Medical Research Council G0700091Medical Research Council MR/M004864/1Medical Research Council MR/N02995X/1Wellcome TrustWellcome Trust GR077544AIA
6 · The paper itself

Abstract

Inflammation-related progressive lung destruction is the leading causes of premature death in cystic fibrosis (CF), a genetic disorder caused by a defective cystic fibrosis transmembrane conductance regulator (CFTR). However, therapeutic targeting of inflammation has been hampered by a lack of understanding of the links between a dysfunctional CFTR and the deleterious innate immune response in CF. Herein, we used a CFTR-depleted zebrafish larva, as an innovative

Indexed as

AnimalsAnimals, Genetically ModifiedCystic Fibrosis Transmembrane Conductance RegulatorImmunity, InnateInflammationNeutrophil InfiltrationWound HealingZebrafishZebrafish ProteinsCFTR protein, zebrafishCystic Fibrosis Transmembrane Conductance RegulatorZebrafish ProteinsapoptosisCFTRcystic fibrosisneutrophilic inflammationneutrophil reverse migrationTanshione IIAtissue repairzebrafish

Identifiers

PMID32849617
PMCPMC7412881
OpenAlexW3046494094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.