Evidence map›Paper›PMID 32849594›Full record

ReviewFrontiers in immunology2020

Formulations for Allergen Immunotherapy in Human and Veterinary Patients: New Candidates on the Horizon.

Isabella Pali-Schöll, Douglas J DeBoer, Claudia Alessandri, Ahmed Adel Seida, Ralf S Mueller, Erika Jensen-Jarolim

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Isabella Pali-SchöllUniversity of Veterinary Medicine, Vienna, Austria.
Douglas J DeBoerDermatology/Allergy Section, Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, United States.
Claudia AlessandriAssociated Centers for Molecular Allergology (CAAM), Rome, Italy.
Ahmed Adel SeidaDepartment of Microbiology and Immunology, Faculty of Veterinary Medicine, Cairo University, Cairo, Egypt.
Ralf S MuellerCentre for Clinical Veterinary Medicine, University of Munich, Munich, Germany.
Erika Jensen-JarolimInstitute of Pathophysiology and Allergy Research, Center of Physiology, Pathophysiology and Immunology, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · ATCairo University · EGUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergen immunotherapy is currently the only causal treatment for allergic diseases in human beings and animals. It aims to re-direct the immune system into a tolerogenic or desensitized state. Requirements include clinical efficacy, safety, and schedules optimizing patient or owner compliance. To achieve these goals, specific allergens can be formulated with adjuvants that prolong tissue deposition and support uptake by antigen presenting cells, and/or provide a beneficial immunomodulatory action. Here, we depict adjuvant formulations being investigated for human and veterinary allergen immunotherapy.

Indexed as

Immune ToleranceAdjuvants, ImmunologicAllergensAnimalsDesensitization, ImmunologicDrug CompoundingHumansHypersensitivityVeterinary DrugsAdjuvants, ImmunologicAllergensVeterinary Drugsadjuvantallergenallergyhumanimmunotherapyveterinary

Identifiers

PMID32849594
PMCPMC7417425
OpenAlexW3047223040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.