Evidence map›Paper›PMID 32849562›Full record

ArticleFrontiers in immunology2020

Androgen-Influenced Polarization of Activin A-Producing Macrophages Accompanies Post-pyelonephritic Renal Scarring.

Teri N Hreha, Christina A Collins, Allyssa L Daugherty, Jessie M Griffith, Keith A Hruska, David A Hunstad

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The immune mechanisms of the urinary tract against infections.Frontiers in cellular and infection microbiology · 2025
    Review
  5. Review
  6. Monocytes and Macrophages in Kidney Disease and Homeostasis.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Uropathogen and host responses in pyelonephritis.Nature reviews. Nephrology · 2023
    Review
  11. Immune defenses in the urinary tract.Trends in immunology · 2023
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Frontiers in genetics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Teri N HrehaDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States.
Christina A CollinsDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States.
Allyssa L DaughertyDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States.
Jessie M GriffithDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States.
Keith A HruskaDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States.
David A HunstadDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States.
Washington University in St. Louis · US

Funding

pan-Genome of E.coli in the bladder and gut of women with recurrent UTIP50DK064540 · NIDDK · WASHINGTON UNIVERSITY · PI HULTGREN, SCOTT J. · 2002 to 2017
$17.9M
RENAL DISEASET32DK007126 · NIDDK · WASHINGTON UNIVERSITY · PI HUMPHREYS, BENJAMIN D. · 1986 to 2022
$5.2M
Novel Advances in the Pathophysiology and Treatment of the CKD-MBDR01DK127186 · NIDDK · WASHINGTON UNIVERSITY · PI HRUSKA, KEITH A · 2021 to 2024
$1.7M
ANDROGEN INFLUENCE ON UTI SUSCEPTIBILITY AND SEVERITYR01DK111541 · NIDDK · WASHINGTON UNIVERSITY · PI HUNSTAD, DAVID · 2018 to 2021
$1.4M
ZEISS LSM880 AIRYSCAN MICROSCOPE FOR SHARED BIOMEDICAL RESEARCHS10OD021629 · OD · WASHINGTON UNIVERSITY · PI FITZPATRICK, JAMES ALEXANDER · 2017 to 2017
$596k
NIDDK NIH HHS P50 DK064540NIDDK NIH HHS R01 DK111541NIDDK NIH HHS R01 DK127186NIDDK NIH HHS T32 DK007126NIH HHS S10 OD021629
6 · The paper itself

Abstract

Ascending bacterial pyelonephritis, a form of urinary tract infection (UTI) that can result in hospitalization, sepsis, and other complications, occurs in ~250,000 US patients annually; uropathogenic

Indexed as

ActivinsAndrogensAnimalsBacterial LoadCytokinesEscherichia coli InfectionsFemaleFibrosisHost-Pathogen InteractionsInflammation MediatorsKidneyMacrophagesMice, Inbred C57BLMice, TransgenicPhenotypePyelonephritisactivin AActivinsAndrogensCytokinesInflammation MediatorsTestosteronetestosterone 17 beta-cypionateactivin AEscherichia colifollistatinmacrophage polarizationurinary tract infection

Identifiers

PMID32849562
PMCPMC7399094
OpenAlexW3046129246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.