Evidence map›Paper›PMID 32849555›Full record

ArticleFrontiers in immunology2020

Developing an Unbiased Multiplex PCR System to Enrich the

Jinghua Wu, Xie Wang, Liya Lin, Xuemei Li, Sixi Liu, Wei Zhang, Lihua Luo, Ziyun Wan, Mingyan Fang, Yi Zhao and 6 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jinghua WuBGI Education Center, University of Chinese Academy of Sciences, Shenzhen, China.
Xie WangBGI-Shenzhen, Shenzhen, China.
Liya LinBGI-Shenzhen, Shenzhen, China.
Xuemei LiBGI-Shenzhen, Shenzhen, China.
Sixi LiuHematology and Oncology Department, Shenzhen Children's Hospital, Shenzhen, China.
Wei ZhangBGI-Shenzhen, Shenzhen, China.
Lihua LuoBGI Education Center, University of Chinese Academy of Sciences, Shenzhen, China.
Ziyun WanBGI-Shenzhen, Shenzhen, China.
Mingyan FangBGI-Shenzhen, Shenzhen, China.
Yi ZhaoBGI-Shenzhen, Shenzhen, China.
Xiaodong WangHematology and Oncology Department, Shenzhen Children's Hospital, Shenzhen, China.
Huirong MaiHematology and Oncology Department, Shenzhen Children's Hospital, Shenzhen, China.
Xiuli YuanHematology and Oncology Department, Shenzhen Children's Hospital, Shenzhen, China.
Feiqiu WenHematology and Oncology Department, Shenzhen Children's Hospital, Shenzhen, China.
Changgang LiHematology and Oncology Department, Shenzhen Children's Hospital, Shenzhen, China.
Xiao LiuBGI-Shenzhen, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate T cell receptor repertoire profiling has provided novel biological and clinical insights in widespread immunological settings; however, there is a lack of reference materials in the community that can be used to calibrate and optimize the various experimental systems in different laboratories. In this study, we designed and synthesized 611 T cell receptor (TCR) beta chain (

Indexed as

Multiplex Polymerase Chain ReactionBiomarkers, TumorClonal EvolutionGene AmplificationHumansLeukemiaNeoplasm, ResidualPrecursor B-Cell Lymphoblastic Leukemia-LymphomaPrecursor Cell Lymphoblastic Leukemia-LymphomaReceptors, Antigen, T-Cell, alpha-betaT-LymphocytesBiomarkers, TumorReceptors, Antigen, T-Cell, alpha-betaimmune repertoireleukemiaminimal residual diseasemultiplex PCR system optimizationTRB

Identifiers

PMID32849555
PMCPMC7423970

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.