Evidence map›Paper›PMID 32849211›Full record

ArticleFrontiers in neurology2020

Traumatic Brain Injury-Induced Sex-Dependent Changes in Late-Onset Sensory Hypersensitivity and Glutamate Neurotransmission.

Gokul Krishna, Caitlin Bromberg, Emily Charlotte Connell, Erum Mian, Chengcheng Hu, Jonathan Lifshitz, P David Adelson, Theresa Currier Thomas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

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  12. Drosophila as a model to explore secondary injury cascades after traumatic brain injury.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Gokul KrishnaDepartment of Child Health, University of Arizona College of Medicine - Phoenix, Phoenix, AZ, United States.
Caitlin BrombergDepartment of Child Health, University of Arizona College of Medicine - Phoenix, Phoenix, AZ, United States.
Emily Charlotte ConnellDepartment of Child Health, University of Arizona College of Medicine - Phoenix, Phoenix, AZ, United States.
Erum MianDepartment of Child Health, University of Arizona College of Medicine - Phoenix, Phoenix, AZ, United States.
Chengcheng HuDepartment of Epidemiology and Biostatistics, University of Arizona, Tucson, AZ, United States.
Jonathan LifshitzDepartment of Child Health, University of Arizona College of Medicine - Phoenix, Phoenix, AZ, United States.
P David AdelsonDepartment of Child Health, University of Arizona College of Medicine - Phoenix, Phoenix, AZ, United States.
Theresa Currier ThomasDepartment of Child Health, University of Arizona College of Medicine - Phoenix, Phoenix, AZ, United States.
University of Arizona · USBarrow Neurological Institute · USPhoenix Children's Hospital · US

Funding

Electrochemical assessment of behaviorally relevant circuit function after TBIR01NS100793 · NINDS · UNIVERSITY OF ARIZONA · PI THOMAS, THERESA CURRIER · 2018 to 2022
$1.7M
NINDS NIH HHS R01 NS100793
6 · The paper itself

Abstract

Women approximate one-third of the annual 2.8 million people in the United States who sustain traumatic brain injury (TBI). Several clinical reports support or refute that menstrual cycle-dependent fluctuations in sex hormones are associated with severity of persisting post-TBI symptoms. Previously, we reported late-onset sensory hypersensitivity to whisker stimulation that corresponded with changes in glutamate neurotransmission at 1-month following diffuse TBI in male rats. Here, we incorporated intact age-matched naturally cycling females into the experimental design while monitoring daily estrous cycle. We hypothesized that sex would not influence late-onset sensory hypersensitivity and associated

Indexed as

behaviorestrousglutamatemicroelectrode arraysneurotransmitterssex differencetraumatic brain injurywhisker

Identifiers

PMID32849211
PMCPMC7419702
OpenAlexW3047227388

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.