Evidence map›Paper›PMID 32849183›Full record

ArticleFrontiers in neurology2020

Longitudinal Stroke Recovery Associated With Dysregulation of Complement System-A Proteomics Pathway Analysis.

Vinh A Nguyen, Nina Riddell, Sheila G Crewther, Pierre Faou, Harinda Rajapaksha, David W Howells, Graeme J Hankey, Tissa Wijeratne, Henry Ma, Stephen Davis and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Vinh A NguyenDepartment of Occupational Therapy, La Trobe University, Bundoora, VIC, Australia.
Nina RiddellDepartment of Psychology and Counselling, La Trobe University, Bundoora, VIC, Australia.
Sheila G CrewtherDepartment of Psychology and Counselling, La Trobe University, Bundoora, VIC, Australia.
Pierre FaouDepartment of Biochemistry and Genetics, La Trobe University, Bundoora, VIC, Australia.
Harinda RajapakshaDepartment of Biochemistry and Genetics, La Trobe University, Bundoora, VIC, Australia.
David W HowellsMedical Sciences Precinct, University of Tasmania, Hobart, TAS, Australia.
Graeme J HankeyFaculty of Health and Medical Sciences, Internal Medicine, University of Western Australia, Perth, WA, Australia.
Tissa WijeratneNeurorehabilitation and Recovery, Stroke, The Florey Institute of Neuroscience and Mental Health, Heidelberg, VIC, Australia.
Henry MaMonash Health, Neurology and Stroke, Clayton, VIC, Australia.
Stephen DavisDepartment of Neurology, Royal Melbourne Hospital, Parkville, VIC, Australia.
Geoffrey A DonnanDepartment of Neurology, Royal Melbourne Hospital, Parkville, VIC, Australia.
Leeanne M CareyDepartment of Occupational Therapy, La Trobe University, Bundoora, VIC, Australia.
La Trobe University · AUFlorey Institute of Neuroscience and Mental Health · AUThe Royal Melbourne Hospital · AUHarry Perkins Institute of Medical Research · AUMonash Health · AUUniversity of Tasmania · AUWestern Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently the longitudinal proteomic profile of post-ischemic stroke recovery is relatively unknown with few well-accepted biomarkers or understanding of the biological systems that underpin recovery. We aimed to characterize plasma derived biological pathways associated with recovery during the first year post event using a discovery proteomics workflow coupled with a topological pathway systems biology approach. Blood samples (

Indexed as

bioinformaticscomplement systemimmune systemlongitudinalpathway analysisproteomicsstrokesystems biology

Identifiers

PMID32849183
PMCPMC7399641
OpenAlexW3046097870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.