ArticleFrontiers in psychology2020
Influence of Stress and Depression on the Immune System in Patients Evaluated in an Anti-aging Unit.
Article in Frontiers in psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- The influence of depression on clinical outcomes of total shoulder arthroplasty: a systematic Review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Pooled it
- The effect of antidepressants on the severity of COVID-19 in hospitalized patients: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Preexisting Depression or Anxiety is Associated with Increased Wound Complications Following Breast Reduction Surgery: A Real-World Cohort Study.Aesthetic plastic surgery · 2026Article
- A network analysis of lifetime stressor exposure, mental health, well-being, and immune cell mobilisation to acute stressors in young adults.Brain, behavior, & immunity - health · 2026Article
- Investigating the Relationship Between Cortisol, a Stress Marker, and Immune Function Across Age and Gender.Cureus · 2025Article
- Constructing a nomogram for ICSI-ET assisted reproductive outcomes in infertile men based on lifestyle and sperm quality: a multicenter retrospective survey.Frontiers in endocrinology · 2025Article
- The impact of behavioral activation on depressive symptoms in colorectal cancer patients within a medical environment: the mediating role of physical activity.American journal of cancer research · 2025Article
- Subchronic administration of scopolamine reverses UCMS-induced behavior in mice via eEF2 protein dephosphorylation.Pharmacological reports : PR · 2024Article
- Severe aspiration pneumonia in the elderly.Journal of intensive medicine · 2024Review
- Palliative Care in the Ageing European Population: A Cross-Country Comparison.International journal of environmental research and public health · 2024Article
- The Potential of Scopolamine as an Antidepressant in Major Depressive Disorder: A Systematic Review of Randomized Controlled Trials.Biomedicines · 2023Review
- Recurrent lower urinary tract infections: more than an infection for older women.Turkish journal of medical sciences · 2023Article
- Diabetes Prevention and Measures to Ensuring a Healthy Lifestyle during COVID-19 Pandemic and after.Korean journal of family medicine · 2023Article
- Association between use of psychotropic medications prior to SARS-COV-2 infection and trajectories of COVID-19 recovery: Findings from the prospective Predi-COVID cohort study.Frontiers in public health · 2023Article
- Feelings of loneliness and isolation: Social brain and social cognition in the elderly and Alzheimer's disease.Frontiers in aging neuroscience · 2022Article
- Case report: Depressive disorder with peripartum onset camouflages suspected intracranial tuberculoma.Frontiers in psychiatry · 2022Article
- Changes in parameters of biochemical and oxidative stress in university students during and after examinations.Cell stress & chaperones · 2021Article
- Interaction Mechanisms Between Major Depressive Disorder and Non-alcoholic Fatty Liver Disease.Frontiers in psychiatry · 2021Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is compelling evidence pointing out that stress and depression produce a dramatic impact on human well-being mainly through impairing the regular function of the immune system and producing a low-chronic inflammation status that favors the occurrence of infections, metabolic diseases, and even cancer. The present work aims to evaluate the stress/depression levels of some patients treated in an antiaging unit and detect any potential relationship with their immune system status prior of the implementation of a physical/psychological program designed to prevent health deterioration.
methodsWe evaluated 48 patients (16 men and 32 women with a mean age of 55.11 ± 10.71 years) from middle-upper class from psychological and immunological points of view. In particular, we analyzed neutrophil chemotaxis and phagocytosis; lymphocyte chemotaxis and proliferation, and natural killer (NK) cell activity.
resultsWomen showed more depressive symptoms than men. Chemotaxis levels of lymphocytes and neutrophils in women showed a significant reduction compared with those in men. We also found a strong negative correlation between depression and NK cell function. This correlation was also significant independently of gender.
conclusionWe conclude that NK activity is affected at least by depression state, and we propose that a combined treatment consisting of cognitive behavioral therapy and physical activity programs might improve patient health deterioration.
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