Evidence map›Paper›PMID 32849047›Full record

ReviewFrontiers in psychology2020

Molecules of Silence: Effects of Meditation on Gene Expression and Epigenetics.

Sabrina Venditti, Loredana Verdone, Anna Reale, Valerio Vetriani, Micaela Caserta, Michele Zampieri

3 registry-linked trialsAbstract readReview
In one paragraph

Review in Frontiers in psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05516355 nacompletednot on this mapstarted 2022, after this paper: background citation

Psychological and Neurobiological Impact of a Retreat Based on Mindfulness and Compassion for Stress Reduction.

TypeinterventionalSponsorUniversidad Complutense de MadridRan2022 to 2022Enrolled49ConditionsMindfulness, Compassion, Psychophysiologic Reaction, Psychological DistressArmsMindfulness-Based Stress Reduction, Compassion Cultivation Training
NCT06091527 narecruitingnot on this mapstarted 2024, after this paper: background citation

Treating Major Depression With Yoga Mono-therapy: 12-Week Randomized Controlled Trial

TypeinterventionalSponsorUniversity of California, San FranciscoRan2024 to 2026Enrolled180ConditionsDepression Mild, Depression ModerateArmsYoga practice, Education
NCT06583395 enrolling by invitationnot on this mapstarted 2021, after this paper: background citation

Effects Of Meditation On The Gut Microbiome And Human Health and Disease

TypeobservationalSponsorTobias Moeller-BertramRan2021 to 2025Enrolled3,000ConditionsAmyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, AsthmaArmsAdvanced multi-component meditation practice
3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sabrina VendittiDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, Rome, Italy.
Loredana VerdoneInstitute of Molecular Biology and Pathology, National Council of Research (CNR), Rome, Italy.
Anna RealeDepartment of Experimental Medicine, Sapienza University, Rome, Italy.
Valerio VetrianiDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, Rome, Italy.
Micaela CasertaInstitute of Molecular Biology and Pathology, National Council of Research (CNR), Rome, Italy.
Michele ZampieriDepartment of Experimental Medicine, Sapienza University, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many studies have consistently demonstrated an epigenetic link between environmental stimuli and physiological as well as cognitive responses. Epigenetic mechanisms represent a way to regulate gene activity in real time without modifying the DNA sequence, thus allowing the genome to adapt its functions to changing environmental contexts. Factors such as lifestyle, behavior, and the practice of sitting and moving mindful activities have been shown to be important means of environmental enrichment. Such practices, which include mindfulness meditation, Vipassana, Yoga, Tai Chi, and Quadrato Motor Training, have been reported to positively impact well-being. In fact, they can be considered emotional and attentional regulatory activities, which, by inducing a state of greater inner silence, allow the development of increased self-awareness. Inner silence can therefore be considered a powerful tool to counteract the negative effects of overabundant environmental noise, thanks to its power to relieve stress-related symptoms. Since all these positive outcomes rely on physiological and biochemical activities, the molecular and epigenetic mechanisms influenced by different mindful practices have recently started to be investigated. Here, we review some of the findings that could allow us to uncover the mechanisms by which specific practices influence well-being.

Indexed as

epigenetic marksepigeneticsgene-expressionmeditationmindfulnesssilence

Identifiers

PMID32849047
PMCPMC7431950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.