Evidence map›Paper›PMID 32848949›Full record

ArticleFrontiers in psychiatry2020

Network Analyses of Maternal Pre- and Post-Partum Symptoms of Depression and Anxiety.

Desiree Y Phua, Helen Chen, Yap Seng Chong, Peter D Gluckman, Birit F P Broekman, Michael J Meaney

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  5. Stable structure, shifting links: How depression-anxiety symptom networks reconfigure from pregnancy to postpartum.European psychiatry : the journal of the Association of European Psychiatrists · 2026
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  11. Major depressive episode and postpartum depression: A network analysis comparison on the IGEDEPP cohort.European psychiatry : the journal of the Association of European Psychiatrists · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Desiree Y PhuaSingapore Institute for Clinical Sciences, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.
Helen ChenDepartment of Psychological Medicine, KK Women's and Children's Hospital, Singapore, Singapore.
Yap Seng ChongSingapore Institute for Clinical Sciences, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.
Peter D GluckmanSingapore Institute for Clinical Sciences, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.
Birit F P BroekmanSingapore Institute for Clinical Sciences, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.
Michael J MeaneySingapore Institute for Clinical Sciences, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.
Agency for Science, Technology and Research · SGDouglas Mental Health University Institute · CAKK Women's and Children's Hospital · SGNational University of Singapore · SGSingapore Institute for Clinical Sciences · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaternal mental health problems often develop prenatally and predict post-partum mental health. However, the circumstances before and following childbirth differ considerably. We currently lack an understanding of dynamic variation in the profiles of depressive and anxiety symptoms over the perinatal period.

methodsDepressive and anxiety symptoms were self-reported by 980 women at 26-week pregnancy and 3 months post-partum. We used network analysis of depressive and anxiety symptoms to investigate if the symptoms network changed during and after pregnancy. The pre- and post-partum depressive-anxiety symptom networks were assessed for changes in structure, unique symptom-symptom interactions, central and bridging symptoms. We also assessed if central symptoms had stronger predictive effect on offspring's developmental outcomes outcomes at birth and 24, 54, and 72 months old than non-central symptoms. Bridging symptoms between negative and positive mental health were also assessed.

resultsThough the depressive-anxiety network structures were stable during and after pregnancy, the post-partum network was more strongly connected. The central depressive-anxiety symptoms were also different between prenatal and post-partum networks. During pregnancy, central symptoms were mostly related to feeling worthless or useless; after pregnancy, central symptoms were mostly related to feeling overwhelmed or being punished. Central symptoms during pregnancy were associated with poorer developmental outcomes for the child. Anxiety symptoms were strongest bridging symptoms during and after pregnancy. The interactions between negative and positive mental health symptoms were also different during and after pregnancy.

conclusionsThe differences between pre- and post-partum networks suggest that the presentation of maternal mental health problems varies over the peripartum period. This variation is not captured by traditional symptom scale scores. The bridging symptoms also suggest that anxiety symptoms may precede the development of maternal depression. Interventions and public health policies should thus be tailored to specific pre- and post-partum symptom profiles.

Indexed as

bridging symptomschild developmentmaternal psychopathologyperinatalpositive mental health

Identifiers

PMID32848949
PMCPMC7424069
OpenAlexW3048317652

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.