Evidence map›Paper›PMID 32848853›Full record

ArticleFrontiers in physiology2020

Acute Aerobic Exercise Remodels the Adipose Tissue Progenitor Cell Phenotype in Obese Adults.

Alison C Ludzki, Emily M Krueger, Toree C Baldwin, Michael W Schleh, Cara E Porsche, Benjamin J Ryan, Lindsey A Muir, Kanakadurga Singer, Carey N Lumeng, Jeffrey F Horowitz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Alison C LudzkiSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, United States.
Emily M KruegerSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, United States.
Toree C BaldwinSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, United States.
Michael W SchlehSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, United States.
Cara E PorscheDepartment of Pediatrics, Medical School, University of Michigan, Ann Arbor, MI, United States.
Benjamin J RyanSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, United States.
Lindsey A MuirDepartment of Computational Medicine and Bioinformatics, Medical School, University of Michigan, Ann Arbor, MI, United States.
Kanakadurga SingerDepartment of Pediatrics, Medical School, University of Michigan, Ann Arbor, MI, United States.
Carey N LumengDepartment of Pediatrics, Medical School, University of Michigan, Ann Arbor, MI, United States.
Jeffrey F HorowitzSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, United States.
University of Michigan–Ann Arbor · US

Funding

TRAINING PROGRAM IN ENDOCRINOLOGY AND METABOLISM.T32DK007245 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RICHARD J. AUCHUS · 1986 to 2026
$7.2M
Insulin sensitivity and fatty acid partitioning in skeletal muscle after exerciseR01DK077966 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOROWITZ, JEFFREY F · 2010 to 2020
$4.9M
The role of iron in adipose tissue lipolysis, systemic fatty acid mobilization, and insulin resistance in obese humansF32DK117522 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RYAN, BENJAMIN · 2018 to 2020
$87k
NIDDK NIH HHS F32 DK117522NIDDK NIH HHS R01 DK077966NIDDK NIH HHS T32 DK007245
6 · The paper itself

Abstract

Adipose tissue pathology in obese patients often features impaired adipogenesis, angiogenesis, and chronic low-grade inflammation, all of which are regulated in large part by adipose tissue stromal vascular cells [SVC; i.e., non-adipocyte cells within adipose tissue including preadipocytes, endothelial cells (ECs), and immune cells]. Exercise is known to increase subcutaneous adipose tissue lipolysis, but the impact of exercise on SVCs in adipose tissue has not been explored. The purpose of this study was to assess the effects of a session of exercise on preadipocyte, EC, macrophage, and T cell content in human subcutaneous adipose tissue. We collected abdominal subcutaneous adipose tissue samples from 10 obese adults (BMI 33 ± 3 kg/m

Indexed as

endothelial cellsexercisemacrophagesobesitypreadipocytesT cells

Identifiers

PMID32848853
PMCPMC7399179
OpenAlexW3045931237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.