Evidence map›Paper›PMID 32848730›Full record

ReviewFrontiers in pharmacology2020

Microalgae as Potential Anti-Inflammatory Natural Product Against Human Inflammatory Skin Diseases.

Wu-Thong Choo, Ming-Li Teoh, Siew-Moi Phang, Peter Convey, Wei-Hsum Yap, Bey-Hing Goh, John Beardall

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 74 citations in OpenAlex.

  1. Bioactive Compounds of Ginger (Antibiotics (Basel, Switzerland) · 2026
    Review
  2. Article
  3. The Effect of Lipid Extract ofMarine drugs · 2025
    Article
  4. Microalgae: revolutionizing skin repair and enhancement.Biotechnology reports (Amsterdam, Netherlands) · 2025
    Review
  5. Article
  6. Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  7. Review
  8. Review
  9. Impact ofCells · 2024
    Article
  10. Article
  11. Antioxidants (Basel, Switzerland) · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Restorative Effect of MicroalgaeInternational journal of molecular sciences · 2023
    Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Wu-Thong ChooSchool of Biosciences, Taylor's University, Lakeside Campus, Subang Jaya, Malaysia.
Ming-Li TeohSchool of Biosciences, Taylor's University, Lakeside Campus, Subang Jaya, Malaysia.
Siew-Moi PhangInstitute of Ocean and Earth Sciences, University of Malaya, Kuala Lumpur, Malaysia.
Peter ConveyBritish Antarctic Survey, NERC, Cambridge, United Kingdom.
Wei-Hsum YapSchool of Biosciences, Taylor's University, Lakeside Campus, Subang Jaya, Malaysia.
Bey-Hing GohBiofunctional Molecule Exploratory Research Group (BMEX), School of Pharmacy, Monash University Malaysia, Bandar Sunway, Malaysia.
John BeardallSchool of Biological Sciences, Monash University, Clayton, VIC, Australia.
Taylor's University · MYBritish Antarctic Survey · GBMonash University · AUMonash University Malaysia · MYUCSI University · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin is the first line of defense against pathogen and other environmental pollutant. The body is constantly exposed to reactive oxygen species (ROS) that stimulates inflammatory process in the skin. Many studies have linked ROS to various inflammatory skin diseases. Patients with skin diseases face various challenges with inefficient and inappropriate treatment in managing skin diseases. Overproduction of ROS in the body will result in oxidative stress which will lead to various cellular damage and alter normal cell function. Multiple signaling pathways are seen to have significant effects during ROS-mediated oxidative stress. In this review, microalgae have been selected as a source of natural-derived antioxidant to combat inflammatory skin diseases that are prominent in today's society. Several studies have demonstrated that bioactive compounds isolated from microalgae have anti-inflammation and anti-oxidative properties that can help remedy various skin diseases. These compounds are able to inhibit production of pro-inflammatory cytokines and reduce the expression of inflammatory genes. Bioactive compounds from microalgae work in action by altering enzyme activities, regulating cellular activities, targeting major signaling pathways related to inflammation.

Indexed as

anti-inflammationanti-oxidantbioactive compoundsmicroalgaeskin disease

Identifiers

PMID32848730
PMCPMC7411303
OpenAlexW3046655343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.