ArticleFrontiers in aging neuroscience2020
Blood-Based Biomarkers for Predictive Diagnosis of Cognitive Impairment in a Pakistani Population.
Article in Frontiers in aging neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Plasma neurofilament light chain is associated with cognitive decline in non-dementia older adults.Scientific reports · 2021Trial
- Serum Molecular Fingerprints of Oxidative Stress Underlying Neurocognitive and Motor Dysfunction in Pesticide-Exposed Populations.The European journal of neuroscience · 2026Article
- Lipidomic signatures reveal biomarkers of mild cognitive impairment.Translational psychiatry · 2026Article
- The Cognitive Changes Among Patients over 65 Years of Age in a Rural Area-The Preliminary Report of Protective and Predisposing Factors.Neurology international · 2025Article
- Trace elements and cognitions in elderly population: a case-control study.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Lipidopathy disrupts peripheral and central amyloid clearance in Alzheimer's disease: Where are our knowledge.IBRO neuroscience reports · 2025Review
- Translating Molecular Psychiatry: From Biomarkers to Personalized Therapies-A Narrative Review.International journal of molecular sciences · 2025Review
- Association of plasma zinc and copper levels with mild cognitive impairment in patients with type 2 diabetes.Frontiers in nutrition · 2025Article
- Associations Between High-Density Lipoprotein Cholesterol Efflux and Brain Grey Matter Volume.Journal of clinical medicine · 2024Article
- Large-scale functional network connectivity mediates the associations between lipids metabolism and cognition in type 2 diabetes.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Association between Serum GDF-15 and Cognitive Dysfunction in Hemodialysis Patients.Biomedicines · 2024Article
- Lipid metabolism and oxidative stress in patients with Alzheimer's disease and amnestic mild cognitive impairment.Brain pathology (Zurich, Switzerland) · 2024Article
- The QPLEX™ Plus Assay Kit for the Early Clinical Diagnosis of Alzheimer's Disease.International journal of molecular sciences · 2023Article
- A Comprehensive Investigation of the Potential Role of Lipoproteins and Metabolite Profile as Biomarkers of Alzheimer's Disease Compared to the Known CSF Biomarkers.International journal of Alzheimer's disease · 2023Article
- Review
- The relationship between levels of physical activity, adherence to the MIND diet, and cognitive impairment in adults aged 65 years or older in Pakistan.Journal of Alzheimer's disease reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Numerous studies have identified an association between age-related cognitive impairment (CI) and oxidative damage, accumulation of metals, amyloid levels, tau, and deranged lipid profile. There is a concerted effort to establish the reliability of these blood-based biomarkers for predictive diagnosis of CI and its progression. We assessed the serum levels of high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, triglycerides, total cholesterol, selected metals (Cu, Al, Zn, Pb, Mn, Cad), and total-tau and amyloid beta-42 protein in mild (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.