ArticleFrontiers in neuroscience2020
Toward Long-Term Communication With the Brain in the Blind by Intracortical Stimulation: Challenges and Future Prospects.
Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 34 citations in OpenAlex.
- Intelligent Visual Prioritization for Retinal Prostheses via Context-Aware Object Ranking and Depth-Aware Phosphene Generation.Biomimetics (Basel, Switzerland) · 2026Article
- Gamification Enhances User Engagement and Task Performance in Prosthetic Vision Testing.Translational vision science & technology · 2026Article
- The unexpected sight: improvement of visual function following intracortical microstimulation of the human occipital cortex.Brain communications · 2026Article
- Gamification Enhances User Engagement and Task Performance in Prosthetic Vision Testing.medRxiv : the preprint server for health sciences · 2025Article
- Neural correlates of phosphene perception in blind individuals: A step toward a bidirectional cortical visual prosthesis.Science advances · 2025Article
- Transparent and Conformal Microcoil Arrays for Spatially Selective Neuronal Activation.Device · 2024Article
- AnFrontiers in neuroscience · 2023Article
- Implications of Neural Plasticity in Retinal Prosthesis.Investigative ophthalmology & visual science · 2022Article
- End-to-end optimization of prosthetic vision.Journal of vision · 2022Article
- Real-world indoor mobility with simulated prosthetic vision: The benefits and feasibility of contour-based scene simplification at different phosphene resolutions.Journal of vision · 2022Article
- Toward a personalized closed-loop stimulation of the visual cortex: Advances and challenges.Frontiers in cellular neuroscience · 2022Article
- Visual percepts evoked with an intracortical 96-channel microelectrode array inserted in human occipital cortex.The Journal of clinical investigation · 2021Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The restoration of a useful visual sense in a profoundly blind person by direct electrical stimulation of the visual cortex has been a subject of study for many years. However, the field of cortically based sight restoration has made few advances in the last few decades, and many problems remain. In this context, the scientific and technological problems associated with safe and effective communication with the brain are very complex, and there are still many unresolved issues delaying its development. In this work, we review some of the biological and technical issues that still remain to be solved, including long-term biotolerability, the number of electrodes required to provide useful vision, and the delivery of information to the implants. Furthermore, we emphasize the possible role of the neuroplastic changes that follow vision loss in the success of this approach. We propose that increased collaborations among clinicians, basic researchers, and neural engineers will enhance our ability to send meaningful information to the brain and restore a limited but useful sense of vision to many blind individuals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.