ArticleJournal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience2020
Chick Embryonic Primary Astrocyte Cultures Provide an Effective and Scalable Model for Authentic Research in a Laboratory Class.
Article in Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Reducing education inequalities through cloud-enabled live-cell biotechnology.Trends in biotechnology · 2025Review
- Internet-Connected Cortical Organoids for Project-Based Stem Cell and Neuroscience Education.eNeuro · 2023Article
- Internet-connected cortical organoids for project-based stem cell and neuroscience education.bioRxiv : the preprint server for biology · 2023Article
- An Undergraduate Laboratory Series UsingJournal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2023Article
- Using Zebrafish Embryos to Study Pharmacological Effects on Neural Development in Hands-On Neurobiology Laboratory Activities.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2022Article
- When the COVID-19 Pandemic Changed Neuroscience Education.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell culture provides an impactful tool for undergraduates to study a range of neurobiological processes. While immortalized or cancer cell lines offer a level of convenience for undergraduate research, particularly for larger scale course-based undergraduate research experiences (CUREs) or project-based learning (PBL), primary cell cultures more closely retain the characteristics of the tissue of origin, allowing students to engage in a wider range of authentic research projects. Astrocytes have gained increasing attention for their role in modulating neuronal viability and are at the forefront of neuroprotection research. Here we describe a method of primary astrocyte culture preparation, derived from embryonic day 8 chicken embryos, optimized for a cell biology laboratory class. The primary astrocytes, prepared and maintained by undergraduates, were used as the model system for student-centered research projects in which students investigated cytoskeletal changes in response to drug treatments. Students reported several learning gains from the experience. The ease of the primary culture method for novice research students allows greater flexibility in designing authentic and scalable research experiences.
Indexed as
Identifiers
32848516PMC7438172W3081355877What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.