Evidence map›Paper›PMID 32848462›Full record

ArticleCancer management and research2020

Hypermethylation of the

Xinghai Wu, Yian Ouyang, Bin Wang, Jian Lin, Yun Bai

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. The correlation between polymorphisms in theTranslational pediatrics · 2021
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xinghai WuDepartment of Neurosurgery, Zhangye People's Hospital Affiliated to Hexi University, Gansu, People's Republic of China.
Yian OuyangDepartment of Neurosurgery, First Affiliated Hospital of Gannan Medical College, Jiangxi, People's Republic of China.
Bin WangDepartment of Neurosurgery, Zhangye People's Hospital Affiliated to Hexi University, Gansu, People's Republic of China.
Jian LinDepartment of Neurosurgery, Zhangye People's Hospital Affiliated to Hexi University, Gansu, People's Republic of China.
Yun BaiDepartment of Neurosurgery, Zhangye People's Hospital Affiliated to Hexi University, Gansu, People's Republic of China.
Hexi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to elucidate the molecular mechanism underlying the involvement of abnormal DNA methylation in the development of glioma and identify potential new targets for glioma therapy.

methodsThe GSE79122 chip achieved from the Gene Expression Omnibus (GEO) database containing 69 glioma samples and 9 normal samples was analyzed. Methylation-specific polymerase chain reaction (MS-PCR or MSP), reverse transcription-PCR, and Western blot analysis were used to confirm the methylation level and expression level of the interleukin receptor-associated kinase (

resultsMicroarray analysis showed that the

conclusion

Indexed as

gliomaIRAK3MAPK signaling pathwaymethylation

Identifiers

PMID32848462
PMCPMC7425661
OpenAlexW3047230803

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.