Evidence map›Paper›PMID 32848305›Full record

ArticleVeterinary world2020

Deleterious effect of short-term gavage of an ethanol extract of cogon grass (

Rini Widyastuti, Sigit Prastowo, Sony H Sumarsono, Alkaustariyah Lubis, Tyagita Hartady, Mas R A A Syamsunarno, Jaqueline Sudiman

Abstract read
In one paragraph

Article in Veterinary world, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Testosterone propionate andInternational journal of reproductive biomedicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rini WidyastutiLaboratory of Animal Reproduction and Artificial Insemination, Department of Animal Production, Faculty of Animal Husbandry, Universitas Padjadjaran, Jl. Raya Bandung - Sumedang km. 21, West Java, Indonesia.
Sigit PrastowoDepartment of Animal Science, Faculty of Agriculture, Universitas Sebelas Maret, Surakarta, Indonesia.
Sony H SumarsonoPhysiology, Developmental Biology and Biomedical Science Research Group, School of Life Science and Technology, Bandung Institute of Technology, Bandung, West Java, Indonesia.
Alkaustariyah LubisUnder Graduate Medical Study Program, Faculty of Medicine, Universitas Padjajaran, Jl. Raya Bandung - Sumedang km. 21, Jatinangor Sumedang, West Java, Indonesia.
Tyagita HartadyDepartment of Biomedical Science, Faculty of Medicine, Universitas Padjadjaran, Jl. Raya Bandung - Sumedang km. 21, Jatinangor Sumedang, West Java, Indonesia.
Mas R A A SyamsunarnoCentral Laboratory, Universitas Padjadjaran, Jl. Raya Bandung - Sumedang km. 21, Jatinangor Sumedang, West Java, Indonesia.
Jaqueline SudimanDepartment of Obstetrics and Gynecology, Faculty of Medicine, Udayana University, Jl. PB. Sudirman, Denpasar, Bali, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimCogon grass ( MATERIALS AND

methodsThis study was designed as completely randomized with three different doses, such as an ethanol extract of CGG roots at 0 (control), 90, and 115 mg/kg body weight. In total, 21 male DDY mice strain were treated with the CGG extract (by gavage) for 14 days, followed by an evaluation of reproductive organs, epididymal sperm quality, testis histology, histomorphometry, and reproductive hormone assays. All quantitative data were analyzed by analysis of variance, followed by Tukey's

resultsThe results showed that the administration of the CGG root ethanol extract disrupted the testis interstitial area and seminiferous tubules, resulting in decreased epididymal sperm quality as well as serum testosterone levels in a dose-dependent pattern.

conclusionOral administration of a CGG root ethanol extract induced testicular damage, decreased epididymal sperm quality, and impaired testosterone secretion.

Indexed as

cogon grass root ethanol extractepididymal sperm qualitymale antifertilityreproductive hormones

Identifiers

PMID32848305
PMCPMC7429374

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.