ArticleVeterinary world2020
A topical ointment formulation containing leaves' powder of
Article in Veterinary world, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 23 citations in OpenAlex.
- Wound Healing Activity ofResearch square · 2026Article
- Histomorphometric analysis of excisional cutaneous wounds with different diameters in an animal model.International journal of experimental pathology · 2024Article
- The Role of Ozonated Jerusalem Artichoke Ointment on the Healing of Surgically Created Full-Thickness Cutaneous Wounds in Rabbits.Veterinary medicine international · 2024Article
- Analytical insights into the detoxification process and characterization of a traditional metallopharmaceutical formulation.RSC medicinal chemistry · 2023Article
- Wound healing properties of green (using Lawsonia inermis leaf extract) and chemically synthesized ZnO nanoparticles in albino rats.Environmental science and pollution research international · 2022Article
- Wound healing by topical application ofVeterinary world · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimMATERIALS AND
methodsTwenty female Wistar rats were used in this study. Excisional wound model was realized by removing skin from the dorsal part of the neck of each animal. Wounds have been then treated by a daily application of LI ointment prepared by mixing leaves' powder to petroleum jelly in test group and by simple application of petroleum jelly in control group. Evaluation of wound healing activity was then based on calculating the percentage of wound contraction, period of epithelialization, and wound index every 3 days for a period of 24 days, then, a histological study of the healed excised wound was performed.
resultsTreatment with LI has shown excellent wound healing activity, since it has increased percent of wound contraction, and reduced period of epithelialization and wound index as compared to control (p<0.05). These results have been supported by the histological findings that revealed better epithelialization, dermal differentiation, collagen fiber orientation, and angiogenesis in LI treated rats compared to control (p<0.05).
conclusionWe can conclude that LI leaves' can be used as a potential wound healing agent.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.