ArticleProceedings of the National Academy of Sciences of the United States of America2020
Detecting selection with a genetic cross.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 34 citations in OpenAlex.
- Natural selection shapes the evolution of the metabolome in Saccharomyces cerevisiae.Molecular biology and evolution · 2026Article
- Divergent and stabilizing selection shape the phenotypic space of Arabidopsis thaliana.PLoS biology · 2025Article
- A genome-to-proteome map reveals how natural variants drive proteome diversity and shape fitness.Science (New York, N.Y.) · 2025Article
- Unique genetic bases of repeated life-history divergence associated with high altitude adaptation inbioRxiv : the preprint server for biology · 2025Article
- Green revolution gene drives adaptation of Arabidopsis to the extremely high altitude.Science China. Life sciences · 2025Article
- Adaptive tail-length evolution in deer mice is associated with differential Hoxd13 expression in early development.Nature ecology & evolution · 2024Article
- The ecology and quantitative genetics of seed and seedling traits in upland and lowland ecotypes of a perennial grass.Evolution letters · 2022Article
- A Pleiotropic Flowering Time QTL Exhibits Gene-by-Environment Interaction for Fitness in a Perennial Grass.Molecular biology and evolution · 2022Article
- Detecting signatures of selection on gene expression.Nature ecology & evolution · 2022Article
- Barcoded bulk QTL mapping reveals highly polygenic and epistatic architecture of complex traits in yeast.eLife · 2022Article
- Evolutionary Ecology of Plant-Arthropod Interactions in Light of the "Omics" Sciences: A Broad Guide.Frontiers in plant science · 2022Review
- Divergent patterns of selection on metabolite levels and gene expression.BMC ecology and evolution · 2021Article
- Caution in testing phenotypic selection.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Reply to Zhang and Xu: Environment is indeed important in any phenotypic study.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
Corrections and comments
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- Erratum issued
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Distinguishing which traits have evolved under natural selection, as opposed to neutral evolution, is a major goal of evolutionary biology. Several tests have been proposed to accomplish this, but these either rely on false assumptions or suffer from low power. Here, I introduce an approach to detecting selection that makes minimal assumptions and only requires phenotypic data from ∼10 individuals. The test compares the phenotypic difference between two populations to what would be expected by chance under neutral evolution, which can be estimated from the phenotypic distribution of an F
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.