Evidence map›Paper›PMID 32848008›Full record

ArticlemSphere2020

A Ceftazidime-Avibactam-Resistant and Carbapenem-Susceptible Klebsiella pneumoniae Strain Harboring

Siqiang Niu, Kalyan D Chavda, Jie Wei, Chunhong Zou, Steven H Marshall, Puneet Dhawan, Deqiang Wang, Robert A Bonomo, Barry N Kreiswirth, Liang Chen

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Characterization of Carbapenem-ResistantInfection and drug resistance · 2026
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  7. Article
  8. KPC-2 allelic variants inMicrobiology spectrum · 2024
    Article
  9. Article
  10. Clinical microbiology reviews · 2023
    Review
  11. Antimicrobial resistance in Gram-negative bacilli in Spain: an experts' view.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2023
    Article
  12. Article
  13. Mobilization of theFrontiers in microbiology · 2023
    Article
  14. Review
  15. Microbiology spectrum · 2022
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Siqiang Niu *Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China siqiangniu@cqmu.edu.cn Liang.Chen@hmh-cdi.org.
Kalyan D Chavda *Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, USA.
Jie WeiDepartment of Laboratory Medicine, West China Second University Hospital, and Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, Sichuan University, Chengdu, China.
Chunhong ZouCollege of Laboratory Medicine, Chongqing Medical University, Yuzhong District, Chongqing, China.
Steven H MarshallResearch Service, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
Puneet DhawanMolecular Resource Facility and Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA.
Deqiang WangCollege of Laboratory Medicine, Chongqing Medical University, Yuzhong District, Chongqing, China.
Robert A BonomoResearch Service, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
Barry N KreiswirthHackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, USA.
Liang ChenHackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, USA siqiangniu@cqmu.edu.cn Liang.Chen@hmh-cdi.org.ORCID 0000-0001-5845-2235
Hackensack Meridian Health · USChongqing Medical University · CNLouis Stokes Cleveland VA Medical Center · USRutgers, The State University of New Jersey · USSichuan University · CNThe Affiliated Yongchuan Hospital of Chongqing Medical University · CN

Funding

The molecular basis of the epidemic blaKPC gene KlebsiellaR01AI090155 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI KREISWIRTH, BARRY NEAL · 2011 to 2021
$7.2M
Understanding B-Lactam Resistance in Acinetobacter baumanniiR01AI072219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ROBERT A. BONOMO, Philip N. Rather · 2007 to 2026
$6.6M
Understanding ceftazidime resistance in SHV B-LactamasesR01AI063517 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A. · 2005 to 2023
$4.9M
A Mechanism-Based Approach to Metallo-beta-Lactamase InhibitionR01AI100560 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A., SPENCER, JAMES · 2012 to 2022
$4.4M
NIAID NIH HHS R01 AI063517NIAID NIH HHS R01 AI072219NIAID NIH HHS R01 AI090155NIAID NIH HHS R01 AI100560
6 · The paper itself

Abstract

Ceftazidime-avibactam is a potent antibiotic combination against

Indexed as

Anti-Bacterial AgentsAzabicyclo CompoundsBacterial Proteinsbeta-LactamasesCarbapenemsCeftazidimeDrug CombinationsDrug Resistance, Multiple, BacterialGenome, BacterialHumansKlebsiella InfectionsKlebsiella pneumoniaeMicrobial Sensitivity TestsNew York CityPlasmidsAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo CompoundsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemsCeftazidimeDrug Combinationsantimicrobial resistancecarbapenemceftazidime-avibactamKPCplasmidselection

Identifiers

PMID32848008
PMCPMC7449627
OpenAlexW3081203806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.