Evidence map›Paper›PMID 32847993›Full record

ArticleOpen heart2020

Worksite intervention study to prevent diabetes in Nepal: a randomised trial protocol.

Prajjwal Pyakurel, Archana Shrestha, Biraj M Karmacharya, Shyam S Budhathoki, Rajendra Kumar Chaudhari, Dipesh Tamrakar, Abha Shrestha, Robin M Karmacharya, Anmol Shrestha, Sumitra Sharma and 2 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Open heart, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04161937 (Work-site Intervention Study to Prevent Diabetes in Nepal), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04161937 naunknown statusnot on this map

Work-site Intervention Study to Prevent Diabetes in Nepal

TypeinterventionalSponsorB.P. Koirala Institute of Health SciencesRan2018 to 2021Enrolled163ConditionsDiabetesArmsBehavioural Intervention
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Prajjwal PyakurelB.P. Koirala Institute of Health Sciences, Dharan, Nepal prazzwal@gmail.com.ORCID 0000-0001-5860-9482
Archana ShresthaKathmandu University School of Medical Sciences, Kathmandu, Nepal.
Biraj M KarmacharyaKathmandu University School of Medical Sciences, Kathmandu, Nepal.
Shyam S BudhathokiGolden Community Hospital, Lalitpur, Nepal.
Rajendra Kumar ChaudhariB.P. Koirala Institute of Health Sciences, Dharan, Nepal.
Dipesh TamrakarKathmandu University School of Medical Sciences, Kathmandu, Nepal.
Abha ShresthaKathmandu University School of Medical Sciences, Kathmandu, Nepal.
Robin M KarmacharyaKathmandu University School of Medical Sciences, Kathmandu, Nepal.
Anmol ShresthaKathmandu University School of Medical Sciences, Kathmandu, Nepal.
Sumitra SharmaKathmadnu Medical College Teaching Hospital, Kathmandu, Nepal.
Sanjib Kumar SharmaB.P. Koirala Institute of Health Sciences, Dharan, Nepal.
Donna SpiegelmanYale School of Public Health, New Haven, Connecticut, USA.
Kathmandu University · NPB.P. Koirala Institute of Health Sciences · NP

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Comprehensive Translational Science Analytics Tools for the Global Health AgendaDP1ES025459 · NIEHS · YALE UNIVERSITY · PI SPIEGELMAN, DONNA L · 2014 to 2018
$4.1M
NCATS NIH HHS UL1 TR001863NIEHS NIH HHS DP1 ES025459
6 · The paper itself

Abstract

introductionIn Nepal, approximately 31% of adult industrial employees have diabetes. While the prevention of type 2 diabetes through behavioural intervention has been disseminated, worksite could be an effective platform for the translation of this knowledge into action as employed adults spend most of their workday waking hours at workplaces. METHODS AND ANALYSIS: We will conduct a randomised controlled trial to assess the effectiveness of a behavioural and a canteen intervention on diabetes risk reduction among those who are prediabetic at two worksites in eastern Nepal. We will recruit 162 adult full-time factory workers with haemoglobin A1c (HbA1c) of 5.7%-6.4% at baseline or fasting blood sugar of 100-125 mg/dL. The 8-14 months' control period will be followed by the behavioural intervention where half of the participants will be randomised to receive the behavioural intervention and half will act as a control and will not receive any intervention. Then, all participants will receive the canteen intervention. The analysis will be intent-to-treat, comparing the difference in the change in HbA1c% between the behavioural intervention group and the control group using a two-sample t-test. The within-participant changes in HbA1c after 6 or more months on the canteen intervention among those not randomised to the behavioural intervention in the previous period will be assessed using the paired t-test. ETHICS AND DISSEMINATION: Ethical approval was obtained from the Institutional Review Board at Yale School of Public Health, New Havens, USA and the Nepal Health Research Council. TRIAL REGISTRATION NUMBER: NCT04161937.

Indexed as

Health BehaviorHealthy LifestyleOccupational Health ServicesPrimary PreventionRisk Reduction BehaviorAdultBiomarkersBlood GlucoseDiabetes MellitusGlycated HemoglobinHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedMulticenter Studies as TopicNepalBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humancoronary artery diseasediabetic heart diseasepublic health

Identifiers

PMID32847993
PMCPMC7451278
OpenAlexW3080299230

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.