Evidence map›Paper›PMID 32847984›Full record

ArticleJournal of the American Society of Nephrology : JASN2020

COVID-19 Infection in Kidney Transplant Recipients: Disease Incidence and Clinical Outcomes.

Michelle Elias, Daniele Pievani, Christine Randoux, Kevin Louis, Blandine Denis, Alexandra Delion, Océane Le Goff, Corinne Antoine, Clarisse Greze, Evangeline Pillebout and 4 more

Open access · greenAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed, 7 pooled it
4.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 7 syntheses or guidelines pooled it, 216 citations in OpenAlex.

  1. Pooled it
  2. COVID-19 and solid organ transplantation: Finding the right balance.Transplantation reviews (Orlando, Fla.) · 2022
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Autologous bone marrow-derived mesenchymal stromal cell therapy with early tacrolimus withdrawal: The randomized prospective, single-center, open-label TRITON study.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Trial
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. The Relative Risk of COVID-19 in Solid Organ Transplant Recipients Over Waves of the Pandemic.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  20. Article

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Michelle EliasKidney Transplant Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France michelle.elias@aphp.fr.
Daniele PievaniKidney Transplant Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Christine RandouxNephrology Department, Bichat Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Kevin LouisParis Translational Research Center for Organ Transplantation, INSERM (Institut National de la Santé et de la Recherche Médicale), UMR-S970, Paris, France michelle.elias@aphp.fr.ORCID 0000-0003-1766-2548
Blandine DenisInfectious Diseases Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Alexandra DelionKidney Transplant Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Océane Le GoffKidney Transplant Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Corinne AntoineKidney Transplant Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Clarisse GrezeNephrology Department, Bichat Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Evangeline PilleboutKidney Transplant Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Imad AbboudKidney Transplant Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.ORCID 0000-0003-4352-1968
Denis GlotzKidney Transplant Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Eric DaugasNephrology Department, Bichat Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Carmen LefaucheurKidney Transplant Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.ORCID 0000-0002-6244-0795
Assistance Publique – Hôpitaux de Paris · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 has been associated with high morbidity and mortality in kidney transplant recipients. However, risk factors for COVID-19 disease in patients with kidney transplants remain poorly defined.

methodsWe enrolled patients who underwent kidney transplantation and were actively followed up in two hospitals in Paris on March 1st, 2020. Patients were screened for baseline and transplant characteristics, functional parameters, comorbidities, and immunosuppressive therapies. COVID-19 disease was assessed. Patients were followed up during the pandemic until April 30th, 2020 by the COVID-19 SLS KT survey program, including teleconsulting, at-home monitoring for patients with COVID-19, and a dedicated phone hotline platform.

resultsAmong 1216 patients with kidney transplants enrolled, 66 (5%) patients were identified with COVID-19 disease, which is higher than the incidence observed in the general population in France (0.3%). Their mean age was 56.4±12.5 years, and 37 (56%) patients were men. The following factors were independently associated with COVID-19 disease: non-White ethnicity (adjusted odds ratio [OR], 2.17; 95% confidence interval [95% CI], 1.23 to 3.78;

conclusionsPatients with kidney transplants display a high risk of mortality. Non-White ethnicity and comorbidities such as obesity, diabetes, asthma, and chronic pulmonary disease were associated with higher risk of developing COVID-19 disease. It is imperative that policy makers urgently ensure the integration of such risk factors on response operations against COVID-19.

Indexed as

ComorbidityOutcome Assessment, Health CareAdultAgedCohort StudiesCoronavirus InfectionsCOVID-19FemaleFranceHumansImmunocompromised HostIncidenceInfection ControlKidney Failure, ChronicKidney TransplantationMalecoronavirusCOVID-19kidney transplantationpandemicSARS-CoV-2

Identifiers

PMID32847984
PMCPMC7609004
OpenAlexW3080263075

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.