Evidence map›Paper›PMID 32847906›Full record

ArticleBMJ open2020

Novel approach to estimate tuberculosis transmission in primary care clinics in sub-Saharan Africa: protocol of a prospective study.

Kathrin Zürcher, Carl Morrow, Julien Riou, Marie Ballif, Anastasia Sideris Koch, Simon Bertschinger, Xin Liu, Manuja Sharma, Keren Middelkoop, Digby Warner and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Safe COBuilding and environment · 2023
    Article
  3. Article
  4. Application of Droplet Digital PCR to Detection ofInfection and drug resistance · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 4 countries.

Kathrin ZürcherInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.ORCID 0000-0002-7915-3194
Carl MorrowDesmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.
Julien RiouInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.
Marie BallifInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.ORCID 0000-0003-3133-3011
Anastasia Sideris KochInstitute of Infectious Disease and Molecular Medicine and the Department of Medicine, University of Cape Town, Rondebosch, Western Cape, South Africa.ORCID 0000-0002-5897-4196
Simon BertschingerInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.
Xin LiuPaul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, Washington, USA.
Manuja SharmaPaul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, Washington, USA.
Keren MiddelkoopDesmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.ORCID 0000-0001-9922-4263
Digby WarnerInstitute of Infectious Disease and Molecular Medicine and the Department of Medicine, University of Cape Town, Rondebosch, Western Cape, South Africa.
Robin WoodDesmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.
Matthias EggerInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.ORCID 0000-0001-7462-5132
Lukas FennerInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland lukas.fenner@ispm.unibe.ch.ORCID 0000-0003-3309-4835
University of Bern · CHDesmond Tutu HIV Foundation · ZAUniversity of Cape Town · ZAUniversity of Washington · US

Funding

Observational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9M
NIAID NIH HHS U01 AI069924
6 · The paper itself

Abstract

introductionTuberculosis (TB) transmission is difficult to measure, and its drivers are not well understood. The effectiveness of infection control measures at healthcare clinics and the most appropriate intervention strategies to interrupt transmission are unclear. We propose a novel approach using clinical, environmental and position-tracking data to study the risk of TB transmission at primary care clinics in TB and HIV high burden settings in sub-Saharan Africa. METHODS AND ANALYSIS: We describe a novel and rapid study design to assess risk factors for airborne TB transmission at primary care clinics in high-burden settings. The study protocol combines a range of different measurements. We will collect anonymous data on the number of patients, waiting times and patient movements using video sensors. Also, we will collect acoustic sound recordings to determine the frequency and intensity of coughing. Environmental data will include indoor carbon dioxide levels (CO ETHICS AND DISSEMINATION: The study was approved by the University of Cape Town (HREC/REF no. 228/2019), the City of Cape Town (ID-8139) and the Ethics Committee of the Canton Bern (2019-02131), Switzerland. The results will be disseminated in international peer-reviewed journals.

Indexed as

TuberculosisHumansPilot ProjectsPrimary Health CareProspective StudiesSouth AfricaSwitzerlandinfectious diseasesprimary carepublic healthtuberculosis

Identifiers

PMID32847906
PMCPMC7451471
OpenAlexW3080630055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.