SynthesisJournal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi2021
Clinical features of neonates born to mothers with coronavirus disease-2019: A systematic review of 105 neonates.
Synthesis in Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Neonatal outcomes and indirect consequences following maternal SARS-CoV-2 infection in pregnancy: a systematic review.BMJ open · 2023Pooled it
- Pooled it
- To mix or not to mix? A rapid systematic review of heterologous prime-boost covid-19 vaccination.Expert review of vaccines · 2021Pooled it
- Pooled it
- Maternal and Neonatal Characteristics and Outcomes of COVID-19 in Pregnancy: An Overview of Systematic Reviews.International journal of environmental research and public health · 2021Pooled it
- COVID-19 and pregnancy: An umbrella review of clinical presentation, vertical transmission, and maternal and perinatal outcomes.PloS one · 2021Pooled it
- Immunohistochemical Analysis of Placental Tissue of Women Infected with SARS-CoV-2 During Pregnancy-A Prospective Clinical Study.International journal of molecular sciences · 2025Article
- SARS-CoV-2 Infection and Its Association with Maternal and Fetal Redox Status and Outcomes: A Prospective Clinical Study.Journal of clinical medicine · 2025Article
- Neonatal outcomes of maternal prenatal coronavirus infection.Pediatric research · 2024Review
- COVID-19's Effect in Pregnancy and Vertical Transmission: A Systematic Review.International journal of preventive medicine · 2024Review
- The Effectiveness of Bivalent COVID-19 Vaccination: A Preliminary Report.Life (Basel, Switzerland) · 2023Review
- Inhibition of IL-6 signaling prevents serum-induced umbilical cord artery dysfunction from patients with severe COVID-19.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Article
- SARS-CoV-2 Transplacental Transmission: A Rare Occurrence? An Overview of the Protective Role of the Placenta.International journal of molecular sciences · 2023Review
- Pregnancy Outcomes in SARS-CoV-2-Positive Patients: A 20-Month Retrospective Analysis of Delivery Cases.Medicina (Kaunas, Lithuania) · 2023Article
- SARS-CoV-2 Infection in Pregnancy: Clues and Proof of Adverse Outcomes.International journal of environmental research and public health · 2023Observational
- Outcome of Newborns with Confirmed or Possible SARS-CoV-2 Vertical Infection-A Scoping Review.Diagnostics (Basel, Switzerland) · 2023Article
- To PCR or not? The impact of shifting policy from PCR to rapid antigen tests to diagnose COVID-19 during the omicron epidemic: a nationwide surveillance study.Frontiers in public health · 2023Article
- Monitoring SARS-CoV-2 seroprevalence over time among pregnant women admitted to delivery units: Suitability for surveillance.PloS one · 2023Article
- Article
- Illness severity indicators in newborns by COVID-19 status in the United States, March-December 2020.Journal of perinatology : official journal of the California Perinatal Association · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite the increasingly recognized impact of novel coronavirus disease (COVID-19), caused by severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), on many aspects of health in adults and children, its effects on neonates born to infected mothers remain unclear. We conducted this study to investigate the outcomes of neonates born to mothers with COVID-19.
methodsWe searched the medical databases from inception to March 31, 2020 to perform a systematic review of outcomes in neonates born to mothers with COVID-19. Data were pooled using a random effects regression model. Primary and secondary outcomes were neonatal clinical outcomes and infectious status, respectively.
resultsFourteen studies involving 105 neonates fulfilling the study criteria were identified. The rates of preterm neonates and those small for gestational age (SGA) were 25 (23.8%) and 10 (11.2%), respectively. Among 91 neonates who were tested, 8 (8.8%) were positive for nucleic acids or antibodies for SARS-CoV-2. Additionally, 28 (26.7%) of the neonates were symptomatic and two test-negative neonates died, including one stillbirth. Between test-positive and test-negative groups, the rates of SGA, preterm delivery, duration between maternal symptom onset and delivery, and perinatal complication were not significantly different; but the rate of symptomatic after birth reached significant difference (62.5% vs 20.5%, p = 0.008).
conclusionsMost neonates born to infected mothers had favorable outcomes. Although direct evidences of intrauterine infection were scarce, the risk of intrauterine infection should be considered based on a positive test in 8.8% of the neonates. Symptomatic neonates born to infected mothers should receive tests for SARS-CoV-2 to initiate appropriate treatment and quarantine. Further studies are warranted to assess the outcomes of COVID-19 in neonates.
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