Evidence map›Paper›PMID 32847075›Full record

ReviewMolecules (Basel, Switzerland)2020

Contiguous Quaternary Carbons: A Selection of Total Syntheses.

Alina Eggert, Christoph Etling, Dennis Lübken, Marius Saxarra, Markus Kalesse

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 13 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Alina EggertInstitut für Organische Chemie, Gottfried Wilhelm Leibniz University Hannover und Biomolekulares Wirkstoffzentrum (BMWZ), Schneiderberg 1B, D-30167 Hannover, Germany.ORCID 0000-0001-6451-8931
Christoph EtlingInstitut für Organische Chemie, Gottfried Wilhelm Leibniz University Hannover und Biomolekulares Wirkstoffzentrum (BMWZ), Schneiderberg 1B, D-30167 Hannover, Germany.
Dennis LübkenInstitut für Organische Chemie, Gottfried Wilhelm Leibniz University Hannover und Biomolekulares Wirkstoffzentrum (BMWZ), Schneiderberg 1B, D-30167 Hannover, Germany.ORCID 0000-0001-9506-1065
Marius SaxarraInstitut für Organische Chemie, Gottfried Wilhelm Leibniz University Hannover und Biomolekulares Wirkstoffzentrum (BMWZ), Schneiderberg 1B, D-30167 Hannover, Germany.ORCID 0000-0002-2380-1500
Markus KalesseInstitut für Organische Chemie, Gottfried Wilhelm Leibniz University Hannover und Biomolekulares Wirkstoffzentrum (BMWZ), Schneiderberg 1B, D-30167 Hannover, Germany.
Leibniz University Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contiguous quaternary carbons in terpene natural products remain a major challenge in total synthesis. Synthetic strategies to overcome this challenge will be a pivotal prerequisite to the medicinal application of natural products and their analogs or derivatives. In this review, we cover syntheses of natural products that exhibit a dense assembly of quaternary carbons and whose syntheses were uncompleted until recently. While discussing their syntheses, we not only cover the most recent total syntheses but also provide an update on the status quo of modern syntheses of complex natural products. Herein, we review (±)-canataxpropellane, (+)-waihoensene, (-)-illisimonin A and (±)-11-

Indexed as

Bridged-Ring CompoundsSesquiterpenes11-O-debenzoyltashironin2alpha,9alpha,10beta-triacetoxy-5alpha-hydroxy-3,11-cyclo-12,20-cyclotaxa-13-oneBridged-Ring Compoundsillisimonin ASesquiterpenescanataxpropellanenatural productsortho-photo-cycloadditiontaxane diterpenetotal synthesiswaihoensene

Identifiers

PMID32847075
PMCPMC7504199
OpenAlexW3080292494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.