Evidence map›Paper›PMID 32847053›Full record

ArticleCancers2020

The Link between Cytogenetics/Genomics and Imaging Patterns of Relapse and Progression in Patients with Relapsed/Refractory Multiple Myeloma: A Pilot Study Utilizing 18F-FDG PET/CT.

Xiang Zhou, Alexander Dierks, Olivia Kertels, Samuel Samnick, Malte Kircher, Andreas K Buck, Larissa Haertle, Sebastian Knorz, David Böckle, Lukas Scheller and 8 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Prognostic value ofAnnals of hematology · 2024
    Article
  6. Head-to-Head Comparison between FDG andDiagnostics (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Xiang ZhouDepartment of Internal Medicine II, University Hospital of Würzburg, Oberdürrbacher Street 6, D-97080 Würzburg, Germany.
Alexander DierksDepartment of Nuclear Medicine, University Hospital of Würzburg, D-97080 Würzburg, Germany.
Olivia KertelsDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, D-97080 Würzburg, Germany.
Samuel SamnickDepartment of Nuclear Medicine, University Hospital of Würzburg, D-97080 Würzburg, Germany.
Malte KircherDepartment of Nuclear Medicine, University Hospital of Würzburg, D-97080 Würzburg, Germany.
Andreas K BuckDepartment of Nuclear Medicine, University Hospital of Würzburg, D-97080 Würzburg, Germany.
Larissa HaertleDepartment of Internal Medicine II, University Hospital of Würzburg, Oberdürrbacher Street 6, D-97080 Würzburg, Germany.
Sebastian KnorzDepartment of Internal Medicine II, University Hospital of Würzburg, Oberdürrbacher Street 6, D-97080 Würzburg, Germany.
David BöckleDepartment of Internal Medicine II, University Hospital of Würzburg, Oberdürrbacher Street 6, D-97080 Würzburg, Germany.
Lukas SchellerDepartment of Internal Medicine II, University Hospital of Würzburg, Oberdürrbacher Street 6, D-97080 Würzburg, Germany.
Janin MesserschmidtDepartment of Internal Medicine II, University Hospital of Würzburg, Oberdürrbacher Street 6, D-97080 Würzburg, Germany.
Mohammad BarakatDepartment of Internal Medicine II, University Hospital of Würzburg, Oberdürrbacher Street 6, D-97080 Würzburg, Germany.
Marietta TrugerMunich Leukemia Laboratory, D-81377Munich, Germany.
Claudia HaferlachMunich Leukemia Laboratory, D-81377Munich, Germany.
Hermann EinseleDepartment of Internal Medicine II, University Hospital of Würzburg, Oberdürrbacher Street 6, D-97080 Würzburg, Germany.
Leo RascheDepartment of Internal Medicine II, University Hospital of Würzburg, Oberdürrbacher Street 6, D-97080 Würzburg, Germany.
K Martin KortümDepartment of Internal Medicine II, University Hospital of Würzburg, Oberdürrbacher Street 6, D-97080 Würzburg, Germany.ORCID 0000-0002-7011-0286
Constantin LapaDepartment of Nuclear Medicine, University Hospital of Würzburg, D-97080 Würzburg, Germany.
Universitätsklinikum Würzburg · DEUniversity Hospital Augsburg · DEMunich Leukemia Laboratory (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Utilizing 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT), we performed this pilot study to evaluate the link between cytogenetic/genomic markers and imaging patterns in relapsed/refractory (RR) multiple myeloma (MM). We retrospectively analyzed data of 24 patients with RRMM who were treated at our institution between November 2018 and February 2020. At the last relapse/progression, patients had been treated with a median of three (range 1-10) lines of therapy. Six (25%) patients showed FDG avid extramedullary disease without adjacency to bone. We observed significantly higher maximum standardized uptake values (SUV

Indexed as

18F-FDG PET/CTmultiple myelomapattern1. Introductionprogressionradiogenomicsrelapse

Identifiers

PMID32847053
PMCPMC7564496
OpenAlexW3080815564

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.