ArticleCancers2020
Combined Targeting of Estrogen Receptor Alpha and Exportin 1 in Metastatic Breast Cancers.
Open access · goldAbstract read
In one paragraph
Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- CD73 inhibitor enhances the antitumor activity of selinexor in multiple myeloma by restoring the activation of CD8Cancer gene therapy · 2026Article
- Co-targeting of metabolism using dietary and pharmacologic approaches reduces breast cancer metastatic burden.NPJ breast cancer · 2025Article
- Selinexor targeting XPO1 promotes PEG3 nuclear accumulation and suppresses cholangiocarcinoma progression.Cancer chemotherapy and pharmacology · 2024Article
- The nuclear export protein exportin-1 in solid malignant tumours: From biology to clinical trials.Clinical and translational medicine · 2024Review
- From metabolism to malignancy: the multifaceted role of PGC1α in cancer.Frontiers in oncology · 2024Review
- Estrogen Receptor Signaling in Breast Cancer.Cancers · 2023Review
- Identification of metabolic pathways contributing to ERScientific reports · 2023Article
- Targeting Metabolic Adaptations in the Breast Cancer-Liver Metastatic Niche Using Dietary Approaches to Improve Endocrine Therapy Efficacy.Molecular cancer research : MCR · 2022Article
- Metabolic Adaptations in an Endocrine-Related Breast Cancer Mouse Model Unveil Potential Markers of Tumor Response to Hormonal Therapy.Frontiers in oncology · 2022Article
- Per- and Polyfluoroalkyl Substance Exposure Combined with High-Fat Diet Supports Prostate Cancer Progression.Nutrients · 2021Article
- Nuclear Receptor-Mediated Metabolic Reprogramming and the Impact on HR+ Breast Cancer.Cancers · 2021Review
- Predicting Bone Metastasis Using Gene Expression-Based Machine Learning Models.Frontiers in genetics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 3 institutions in 1 country.
Eylem Kulkoyluoglu CotulDepartment of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0003-2398-2441
Qianying ZuoDepartment of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0002-3288-2672
Ashlie Santaliz-CasianoDivision of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Ozan Berk ImirDivision of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Ayca Nazli MogolDivision of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Elif TuncDepartment of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Kevin DuongDepartment of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0001-8447-9642
Jenna Kathryn LeeDepartment of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Rithva RameshDepartment of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Elijah OdukoyaDepartment of Human Development and Family Studies, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Mrinali P KesavadasDepartment of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Monika ZiogaiteDepartment of Interdisciplinary Health Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0003-2306-5782
Brandi Patrice SmithDepartment of Informatics, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0001-7686-5105
Chengjian MaoDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
David J ShapiroDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Ben Ho ParkDivision of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Benita S KatzenellenbogenCancer Center at Illinois, Urbana, IL 61801, USA.ORCID 0000-0002-8847-2752
Drew DalyXylyx Bio, Inc., Brooklyn, NY 11226, USA.
Evelyn ArandaXylyx Bio, Inc., Brooklyn, NY 11226, USA.
John D O'NeillXylyx Bio, Inc., Brooklyn, NY 11226, USA.ORCID 0000-0002-1812-2247
Christopher WalkerKaryopharm Therapeutics, Newton, MA 02459, USA.
Yosef LandesmanKaryopharm Therapeutics, Newton, MA 02459, USA.
Zeynep Madak-ErdoganDepartment of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0003-2607-1643
University of Illinois Urbana-Champaign · USKaryopharm Therapeutics (United States) · USVanderbilt University Medical Center · US
Funding
Targeting Breast Cancer with Small Molecule Inhibitors of Estrogen ReceptorR01DK071909 · NIDDK · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI SHAPIRO, DAVID J · 2005 to 2020
$4.3MChemical, structural and molecular rules for fully antagonizing the estrogen receptorR01CA220284 · NCI · UNIVERSITY OF FLORIDA · PI KATZENELLENBOGEN, BENITA S, KATZENELLENBOGEN, JOHN A. · 2018 to 2022
$2.8MBreast Cancer Research Foundation 19-083Cancer Center at Illinois Seed grantKaryopharm Therapeutics Investigator Initiated GrantNational Institute of Food and Agriculture ILLU-698-909NCI NIH HHS 1R01CA220284NIDDK NIH HHS R01 DK071909NIDDK NIH HHS R01DK071909University of Illinois, Urbana-Champaign Research Board RB17083
Abstract
The majority of breast cancer specific deaths in women with estrogen receptor positive (ER
Indexed as
breast cancercombination therapiesESR1 mutant modelsglutaminemetabolic rewiringselinexortamoxifen
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.