ArticleChildren (Basel, Switzerland)2020
High BAL sRAGE is Associated with Low Serum Eosinophils and IgE in Children with Asthma.
Article in Children (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Predictors of asthma exacerbations in children with or without house dust mite allergy.International journal of occupational medicine and environmental health · 2026Observational
- Neutrophils and Asthma.Diagnostics (Basel, Switzerland) · 2022Review
- TSLP bronchoalveolar lavage levels at baseline are linked to clinical disease severity and reduced lung function in children with asthma.Frontiers in pediatrics · 2022Article
- Positive bronchoalveolar lavage pepsin assay associated with viral and fungal respiratory infections in children with chronic cough.Pediatric pulmonology · 2021Article
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Authors and funding
4 authors.
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Abstract
Asthma remains the most common chronic lung disease in childhood in the United States. The receptor for advanced glycation end products (RAGE) has been recognized as both a marker of and participant in pulmonary pathophysiology. While membrane-bound RAGE (mRAGE) perpetuates the type 2 immune response, the soluble form (sRAGE) may act as a decoy receptor for pro-inflammatory ligands. Bronchoalveolar samples from 45 pediatric patients with asthma were obtained. Patients were divided into high and low BAL sRAGE groups using median sRAGE. Descriptive statistical analysis and non-parametric testing were applied. Children in the "high" sRAGE group had a lower median serum eosinophil (0.27 [SE ± 0.04] vs. 0.57 [± 0.06] K/mcl, adjusted
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