Evidence map›Paper›PMID 32845718›Full record

ArticleAmerican journal of physiology. Cell physiology2020

Coordinate adaptations of skeletal muscle and kidney to maintain extracellular [K

Brandon E McFarlin, Yuhan Chen, Taylor S Priver, Donna L Ralph, Adriana Mercado, Gerardo Gamba, Meena S Madhur, Alicia A McDonough

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Cell physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. KiScience · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Potassium homeostasis: sensors, mediators, and targets.Pflugers Archiv : European journal of physiology · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Rapid development of vasopressin resistance in dietary KAmerican journal of physiology. Renal physiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Brandon E McFarlinDepartment of Physiology and Neuroscience, Keck School of Medicine of the University of Southern California, Los Angeles, California.ORCID 0000-0003-3829-4609
Yuhan ChenDivision of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee.
Taylor S PriverDepartment of Physiology and Neuroscience, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Donna L RalphDepartment of Physiology and Neuroscience, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Adriana MercadoDepartment of Nephrology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.ORCID 0000-0002-6881-0160
Gerardo GambaMolecular Physiology Unit, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Meena S MadhurDivision of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee.
Alicia A McDonoughDepartment of Physiology and Neuroscience, Keck School of Medicine of the University of Southern California, Los Angeles, California.ORCID 0000-0002-0459-469X
University of Southern California · USInstituto Nacional de Cardiología · MXInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXNanjing University · CNVanderbilt University Medical Center · US

Funding

Sodium transporter regulation during hypertensionR01DK083785 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AURELIE EDWARDS, Alicia A. McDonough · 2011 to 2026
$5.8M
Immunophenotyping of Human Hypertension Using Single Cell Multiplex Mass Cytometry to Identify Novel Therapeutic TargetsDP2HL137166 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MADHUR, MEENAKSHI SWAMINATHAN · 2016 to 2021
$2.8M
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2R01DK083785NHLBI NIH HHS DP2 HL137166NIDDK NIH HHS R01 DK083785
6 · The paper itself

Abstract

Extracellular fluid (ECF) potassium concentration ([K

Indexed as

Adaptation, PhysiologicalAnimalsBlood PressureEpithelial Sodium ChannelsExtracellular FluidHumansHypertensionK Cl- CotransportersKcnj10 ChannelKidneyMiceMuscle, SkeletalPhosphorylationPotassiumPotassium Channels, Inwardly RectifyingProtein Serine-Threonine KinasesEpithelial Sodium ChannelsK Cl- CotransportersKcnj10 ChannelOsr1 protein, mousePotassiumPotassium Channels, Inwardly RectifyingProtein Serine-Threonine KinasesSodium-Potassium-Chloride SymportersSolute Carrier Family 12, Member 2Stk39 protein, mouseSymportersTranscription FactorsKCC3NCCNKCC1NKCC2sodium pump α2-β2

Identifiers

PMID32845718
PMCPMC7654654
OpenAlexW3080233428

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.