ArticleEnvironmental science and pollution research international2021
Regulation of glutathione-dependent antioxidant defense system of grass carp Ctenopharyngodon idella under the combined stress of mercury and temperature.
Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 10 citations in OpenAlex.
- Article
- Acclimation during Embryogenesis Remodulates Telomerase Activity and Gene Expression in Baikal Whitefish Larvae, Mitigating the Effects of Acute Temperature Stress.Animals : an open access journal from MDPI · 2024Article
- Association between Pb, Cd, and Hg Exposure and Liver Injury among Korean Adults.International journal of environmental research and public health · 2021Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
In this study, we investigated the combined effects of temperatures fluencies and mercury (Hg) on glutathione-dependent antioxidant system in fish, by measuring the oxidative stress indicator (LPO, lipid peroxidation) and the parameters involved in the glutathione-related antioxidant defense system (GPx, glutathione peroxidase; GR, glutathione reductase; GST, glutathione S-transferase; GSH, reduced glutathione), as well as the expression of related genes in grass carp, Ctenopharyngodon idella. Fish (45.37 ± 3.58 g) were exposed to 10 test groups, e.g., 15 °C with/without Hg, 20 °C with/without Hg, 25 °C with/without Hg, 30 °C with/without Hg, 35 °C with/without Hg for 4 weeks. Three-way ANOVA was used to analyze the correlation between the measured parameters and experimental conditions (water temperature, Hg exposure, exposure time, and their interactions.). Our results show that there is no interaction between mercury and low temperature, but the combined effect at high temperature has been confirmed, which indicated the glutathione-dependent enzyme system in grass carp has a complex regulatory mechanism with temperature fluctuations. In the actual field monitoring, it is necessary to consider the impact of extreme temperature on the toxicity of pollutants in the aquatic ecosystem.
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Registered trials
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