Evidence map›Paper›PMID 32845423›Full record

ArticleJournal of autism and developmental disorders2021

Composite Sleep Problems Observed Across Smith-Magenis Syndrome, MBD5-Associated Neurodevelopmental Disorder, Pitt-Hopkins Syndrome, and ASD.

Anusha Gandhi, Dihong Zhou, Joseph Alaimo, Edwin Chon, Michael D Fountain, Sarah H Elsea

Abstract read
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In one paragraph

Article in Journal of autism and developmental disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Anusha GandhiDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA. anusha.gandhi@bcm.edu.
Dihong ZhouDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.
Joseph AlaimoDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.
Edwin ChonDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.
Michael D FountainDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.
Sarah H ElseaDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA. elsea@bcm.edu.ORCID http://orcid.org/0000-0002-1400-8519
Baylor College of Medicine · USChildren's Mercy Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caregivers of preschool and elementary school age children with Smith-Magenis syndrome (SMS), MBD5-associated neurodevelopmental disorder (MAND), and Pitt-Hopkins syndrome (PTHS) were surveyed to assess sleep disturbance and to identify disorder-specific sleep problems. Because of overlapping features of these rare genetic neurodevelopmental syndromes, data were compared to reports of sleep disturbance in children with autism spectrum disorder (ASD). While similarities were observed with ASD, specific concerns between disorders differed, including mean nighttime sleep duration, daytime sleepiness, night wakings, parasomnias, restless sleep, and bedwetting. Overall, sleep disturbance in PTHS is significant but less severe than in SMS and MAND. The complexity of these conditions and the challenges of underlying sleep disturbance indicate the need for more support, education, and ongoing management of sleep for these individuals.

Indexed as

Autism Spectrum DisorderChildChild, PreschoolDNA-Binding ProteinsFaciesFemaleHumansHyperventilationIntellectual DisabilityMaleNeurodevelopmental DisordersSleepSleep Wake DisordersSmith-Magenis SyndromeDNA-Binding ProteinsMBD5 protein, humanAutism spectrum disorderMBD5-associated neurodevelopmental disorderNeurodevelopmental disorderPitt–Hopkins syndromeSleep disturbanceSmith–Magenis syndrome

Identifiers

PMID32845423
OpenAlexW3080462680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.