Evidence map›Paper›PMID 32845413›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2020

Children account for a small proportion of diagnoses of SARS-CoV-2 infection and do not exhibit greater viral loads than adults.

Philippe Colson, Hervé Tissot-Dupont, Aurélie Morand, Céline Boschi, Laetitia Ninove, Vera Esteves-Vieira, Philippe Gautret, Philippe Brouqui, Philippe Parola, Jean-Christophe Lagier and 4 more

Abstract read
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  7. Article
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  12. How useful is serology for COVID-19?International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Temporal and age distributions of SARS-CoV-2 and other coronaviruses, southeastern France.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
  17. Review
  18. SARS-CoV-2 infections in children and young people.Clinical immunology (Orlando, Fla.) · 2020
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Philippe ColsonIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
Hervé Tissot-DupontIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
Aurélie MorandIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
Céline BoschiIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
Laetitia NinoveIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
Vera Esteves-VieiraIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
Philippe GautretIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
Philippe BrouquiIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
Philippe ParolaIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
Jean-Christophe LagierIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
Christine ZandottiIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
Matthieu MillionIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
Bernard La ScolaIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
Didier RaoultIHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France. didier.raoult@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous reports have suggested that children are less affected than adults by SARS-CoV-2. We analyzed SARS-CoV-2 diagnoses between February 27, 2020, and March 14, 2020, and mortality among positive patients in Marseille university hospitals. Of 4050 tested individuals, 228 were positive. Deaths occurred in 2/99 documented cases (both > 85 year-old). Children were majorly asymptomatic. Incidence increased by 7.4-fold between 1-5 and 45-65 years then decreased. It was significantly lower among 0-1 year- (0%) and 1-5 (1.1%) and 5-10 (3.6%)-year-old children than among subjects > 18 years (6.5%). Viral loads did not differ between children and adults. Children may not contribute significantly to virus circulation.

Indexed as

PandemicsViral LoadAdolescentAdultAgedAged, 80 and overAge FactorsAsymptomatic DiseasesBetacoronavirusChildChild, PreschoolClinical Laboratory TechniquesCoronavirus InfectionsCOVID-19COVID-19 TestingFemaleChildrenCovid-19SARS-CoV-2TransmissionViral load

Identifiers

PMID32845413
PMCPMC7447969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.