Evidence map›Paper›PMID 32845406›Full record

ArticleEJNMMI research2020

Impact of the Q.Clear reconstruction algorithm on the interpretation of PET/CT images in patients with lymphoma.

Michał Wyrzykowski, Natalia Siminiak, Maciej Kaźmierczak, Marek Ruchała, Rafał Czepczyński

Abstract read
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Article in EJNMMI research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. β1600 Q.Clear Digital Reconstruction of [Journal of clinical medicine · 2024
    Article
  9. Article
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  14. Optimizing Low-Dose [18F]FDG-PET/CT Scans: Ensuring Quality Amid Radiotracer Availability Challenges - Insights from a Peripheral Tertiary Care Center.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
    Article
4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Michał WyrzykowskiDepartment of Nuclear Medicine, Affidea Poznań, Poznań, Poland. mich.wyrzykowski@gmail.com.ORCID http://orcid.org/0000-0002-5971-2868
Natalia SiminiakDepartment of Endocrinology and Metabolism, Poznan University of Medical Sciences, Poznań, Poland.
Maciej KaźmierczakDepartment of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznań, Poland.
Marek RuchałaDepartment of Endocrinology and Metabolism, Poznan University of Medical Sciences, Poznań, Poland.
Rafał CzepczyńskiDepartment of Nuclear Medicine, Affidea Poznań, Poznań, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQ.Clear is a new Bayesian penalized-likelihood PET reconstruction algorithm. It has been documented that Q.Clear increases the SUVmax values of different malignant lesions. PURPOSE: SUVmax values are crucial for the interpretation of PET/CT images in patients with lymphoma, particularly when the early and final responses to treatment are evaluated. The aim of the study was to systematically analyse the impact of the use of Q.Clear on the interpretation of PET/CT in patients with lymphoma.

methodsA total of 280

resultsThe stage of lymphoma was concordantly diagnosed in 69/70 patients with both algorithms on sPET. Discordant assessment of the Deauville score (p < 0.001) was found in 11 cases (15.7%) of 70 iPET scans and in 11 cases of 70 ePET scans. An upgrade from a negative to a positive scan by Q.Clear occurred in 3 cases (4.3%) of iPET scans and 7 cases (10.0%) of ePET scans. The results of all 70 rPET scans were concordant. The SUVmax values of the target lymphoma lesions measured with Q.Clear were higher than those measured with OSEM in 88.8% of scans.

conclusionAlthough the Q.Clear algorithm may alter the interpretations of PET/CT in only a small proportion of patients, we recommend using standard OSEM reconstruction for the assessment of treatment response.

Indexed as

Deauville criteriaLymphomaPET/CTQ.ClearReconstruction algorithm

Identifiers

PMID32845406
PMCPMC7450027

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.