Evidence map›Paper›PMID 32845239›Full record

ArticleeLife2020

m6A RNA methylation impacts fate choices during skin morphogenesis.

Linghe Xi, Thomas Carroll, Irina Matos, Ji-Dung Luo, Lisa Polak, H Amalia Pasolli, Samie R Jaffrey, Elaine Fuchs

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. TheGenes · 2026
    Article
  5. Article
  6. Article
  7. RNA NCell death & disease · 2025
    Article
  8. NZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  9. Epigenetic orchestration of RNA mInternational journal of biological sciences · 2025
    Review
  10. Review
  11. Review
  12. Science advances · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. Mettl3-catalyzed mScience advances · 2023
    Article
  17. ALKBH5-mediated mInflammation and regeneration · 2023
    Article
  18. Research Progress of mBioMed research international · 2023
    Review
  19. [Research advances on the effects of RNA NZhonghua shao shang yu chuang mian xiu fu za zhi · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Linghe XiHoward Hughes Medical Institute, Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, United States.ORCID 0000-0002-1239-5316
Thomas Carroll *Bioinformatics Resource Center, The Rockefeller University, New York, United States.
Irina Matos *Howard Hughes Medical Institute, Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, United States.ORCID 0000-0001-6100-8020
Ji-Dung LuoBioinformatics Resource Center, The Rockefeller University, New York, United States.ORCID 0000-0003-0150-1440
Lisa PolakHoward Hughes Medical Institute, Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, United States.
H Amalia PasolliElectron Microscopy Resource Center, The Rockefeller University, New York, United States.
Samie R JaffreyDepartment of Pharmacology, Weill Cornell Medicine, Cornell University, New York, United States.ORCID 0000-0003-3615-6958
Elaine FuchsHoward Hughes Medical Institute, Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, United States.ORCID 0000-0002-0978-5137
Howard Hughes Medical Institute · USRockefeller University · USCornell University · US

Funding

VITAMIN A AND KERATINIZATION IN HUMAN EPITHELIAL CELLSR01AR031737 · NIAMS · UNIVERSITY OF CHICAGO · PI ELAINE FUCHS · 1986 to 2026
$16.6M
New mechanisms and technologies for understanding post-transcriptional gene regulation in neuronsR35NS111631 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI SAMIE R JAFFREY · 2019 to 2026
$8.6M
Mechanisms of epitranscriptomic regulation in cancerR01CA186702 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SAMIE R JAFFREY, Michael Kharas · 2014 to 2026
$8.0M
GENE EXPRESSION &DIFFERENTIATION IN HUMAN EPIDERMISR01AR027883 · NIAMS · UNIVERSITY OF CHICAGO · PI FUCHS, ELAINE · 1986 to 2022
$7.6M
Uncovering the role of m6A in the melanocyte response to ultraviolet lightR21CA224391 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI JAFFREY, SAMIE R, ZIPPIN, JONATHAN HALE · 2018 to 2019
$399k
Damon Runyon Cancer Research Foundation DRG-2263-16Howard Hughes Medical InstituteNCI NIH HHS R01 CA186702NCI NIH HHS R21 CA224391NIAMS NIH HHS R01 AR027883NINDS NIH HHS R35 NS111631
6 · The paper itself

Abstract

N

Indexed as

RNA, MessengerSkinAdenosineAnimalsComputational BiologyFemaleMethylationMethyltransferasesMiceOrganogenesisSignal TransductionTranscriptome6-methyladenine mRNA methyltransferaseAdenosineMethyltransferasesN-methyladenosineRNA, Messengerdevelopmental biologylineage specificationmiCLIPmouseN6-methyladenosineRNA metabolismskin epithelial morphogenesis

Identifiers

PMID32845239
PMCPMC7535931
OpenAlexW3081274805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.