ReviewReviews in medical virology2021
Predictors of COVID-19 severity: A literature review.
Review in Reviews in medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 510 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
510 citing papers in PubMed, 3 syntheses or guidelines pooled it, 869 citations in OpenAlex.
- A Systematic Review of Predictor Composition, Outcomes, Risk of Bias, and Validation of COVID-19 Prognostic Scores.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Pooled it
- Multidisciplinary inpatient rehabilitation for older adults with COVID-19: a systematic review and meta-analysis of clinical and process outcomes.BMC geriatrics · 2023Pooled it
- Global prevalence of coronavirus disease 2019 reinfection: a systematic review and meta-analysis.BMC public health · 2023Pooled it
- Predictors of COVID-19 vaccination status among youth in eThekwini, South Africa: results from the AYAZAZI RIGHTS study.Global health action · 2026Article
- Identifying Demographic Predictors of Increased Nonfatal Opioid Overdose Risk Among New York State Medicaid Enrollees After the COVID-19 Pandemic: An Analysis of Heterogeneous Treatment Effects.Epidemiology (Cambridge, Mass.) · 2026Article
- Comparative study of post- COVID-19 Kawasaki disease and multisystem inflammatory syndrome cases at Alexandria University Children's Hospital.BMC pediatrics · 2026Article
- Inflammatory Biomarkers as Mediators of the Effect Between High-Dose Corticosteroid Therapy and Mortality in COVID-19-Related ARDS: A Causal Mediation Analysis.Immunity, inflammation and disease · 2026Article
- Racial and Ethnic Differences in COVID-19 Disease Severity Among US Adults in Health Systems Participating in PCORnet®: May 2020-October 2022.Medical care · 2026Article
- Observational
- Demonstration of CMOS-compatible memristor-based electrochemical biosensor transducer with threshold-sensing functionality.Nature communications · 2025Article
- Being in postmenopause may be associated with lower prevalence of COVID-19 symptoms among women over 45 years of age with and without HIV.Menopause (New York, N.Y.) · 2025Article
- Laboratory changes and clinical correlates of disease severity in hospitalized pregnant women with COVID-19.Annals of medicine and surgery (2012) · 2025Article
- A comparative clinical features of COVID-19 in Non-elderly adult and elderly populations of Kermanshah province in Iran: a retrospective study.BMC infectious diseases · 2025Article
- Clinical Evaluation of COVID-19 Survivors at a Public Multidisciplinary Health Clinic.Biomedicines · 2025Article
- Imaging and Laboratory Results as Predictors of the Course of COVID-19.Advances in respiratory medicine · 2025Article
- Gut microbiota alterations are linked to COVID-19 severity in North African and European populations.NPJ biofilms and microbiomes · 2025Article
- The Role of Serial Monitoring of Laboratory Parameters in Determining the Need for Intensive Care in Severe COVID-19: A Single-Center Retrospective Study.Infectious diseases & clinical microbiology · 2025Article
- ACCREDIT: Validation of clinical score for progression of COVID-19 while hospitalized.Global epidemiology · 2025Article
- Evaluation of selected inflammatory markers in cats with feline infectious peritonitis before and after therapy.BMC veterinary research · 2025Article
- How inclusive were strategies to prevent the spread of COVID-19 for people with disabilities? Evidence from qualitative research in eight low- and middle-income countries.International journal for equity in health · 2025Article
450 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
The coronavirus disease 2019 (COVID-19) pandemic is a rapidly evolving global emergency that continues to strain healthcare systems. Emerging research describes a plethora of patient factors-including demographic, clinical, immunologic, hematological, biochemical, and radiographic findings-that may be of utility to clinicians to predict COVID-19 severity and mortality. We present a synthesis of the current literature pertaining to factors predictive of COVID-19 clinical course and outcomes. Findings associated with increased disease severity and/or mortality include age > 55 years, multiple pre-existing comorbidities, hypoxia, specific computed tomography findings indicative of extensive lung involvement, diverse laboratory test abnormalities, and biomarkers of end-organ dysfunction. Hypothesis-driven research is critical to identify the key evidence-based prognostic factors that will inform the design of intervention studies to improve the outcomes of patients with COVID-19 and to appropriately allocate scarce resources.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.